耗材描述
Phytol
产品活性:Phytol ((E)-Phytol) 是一种具有口服活性的可从叶绿素中提取的二萜醇。Phytol 具有抗氧化、抗炎、抗血吸虫和抗菌 (antibacterial) 活性。
产品来源: https://www.medchemexpress.cn/phytol.html
研究领域:Anti-infection | NF-κB
作用靶点:Parasite | Bacterial | Keap1-Nrf2
来源:植物 | 银杏科 | 银杏
结构分类:萜类 | 二萜 | 结构分类
In Vitro: Phytol (50-100 μg/mL, 48 h) reduces the motor activity of worms and causes their death.
Phytol (40 μM, 2 h) inhibits osteoclast differentiation and oxidative stress of RAW264.7 cells induced by RANKL by regulating Nrf2/HO-1.
In Vivo: Phytol (40 mg/kg, orally, for 2 weeks) can reduce the number of parasites in mice infected with adult C. mansoni.
Phytol (10 or 20 mg/kg, orally, for 4 consecutive days) can improve anemia and oxidative brain damage in Plasmodium bergsii infected mice.
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