Myristicin 产品活性：Myristicine 是血清素受体拮抗剂和弱的单胺氧化酶 (MAO) 抑制剂，具有口服生物活性。Myristicine 还通过抑制 EGFR/ERK 信号通路发挥对胃癌细胞的抗癌作用。Myristicine 是肉豆蔻精油的主要成分，具有抗癌、抗增殖、抗菌、抗炎和诱导凋亡 (apoptosis) 的作用。Myristicine 滥用会产生致幻作用，器官损伤等。 产品来源： https://www.medchemexpress.cn/myristicin.html 研究领域：GPCR/G Protein | Stem Cell/Wnt | JAK/STAT Signaling | MAPK/ERK Pathway | Neuronal Signaling | Protein Tyrosine Kinase/RTK | Apoptosis | Anti-infection 作用靶点：5-HT Receptor | ERK | EGFR | Apoptosis | Bacterial 来源：植物 | 肉豆蔻科 | 肉豆蔻 结构分类：苯丙素类 | 简单苯丙素 | 结构分类 In Vitro: Myristicin (7.8-31.25 μM; 48 h) can delay the proliferation of gastric cancer cells and induce endoplasmic reticulum (ER) stress and apoptosis; at the same time, Myristicin reduces the expression of cell cycle proteins, increases the expression of Bax, and activates caspase enzyme, and enhances the release of cytochrome C and mitochondrial ROS levels . In Vivo: In animal models, Myristicin can inhibit the growth of gastric cancer cells and the EGFR/ERK signaling pathway.Myristicin (200 mg/kg; po; single dose) treated 6 hours in advance, on acetic acid (AA)-induced small Mouse experimental colitis model has preventive and protective effect. 相关产品：Natural Product Library Plus | Bioactive Compound Library Plus | Anti-Infection Compound Library | Apoptosis Compound Library | GPCR/G Protein Compound Library | Immunology/Inflammation Compound Library | JAK/STAT Compound Library | Kinase Inhibitor Library | MAPK Compound Library | Neuronal Signaling Compound Library | Protein Tyrosine Kinase Compound Library | Stem Cell Signaling Compound Library | Natural Product Library | Anti-Cancer Compound Library | Anti-Aging Compound Library | Differentiation Inducing Compound Library | Reprogramming Compound Library | Oxygen Sensing Compound Library | Antibacterial Compound Library | Endoplasmic Reticulum Stress Compound Library | Medicine Food Homology Compound Library | Orally Active Compound Library | Neurotransmitter Receptor Compound Library | Glutamine Metabolism Compound Library | Traditional Chinese Medicine Active Compound Library | Anti-Alzheimer's Disease Compound Library | Anti-Hepatitis C Virus Compound Library | Anti-Lung Cancer Compound Library | Anti-Pancreatic Cancer Compound Library | Gut Microbial Metabolite Library | Anti-Parkinson's Disease Compound Library | Neurodegenerative Disease-related Compound Library | Anti-Obesity Compound Library | Angiogenesis-Related Compound Library | Food-Sourced Compound Library | Anti-Liver Cancer Compound Library | Anti-Colorectal Cancer Compound Library | Anti-Cancer Natural Product Library | Anti-inflammatory Traditional Chinese Medicine Active Compound Library | Plant-Sourced Natural Product Library | 5-HT Receptor Compound Library | Human Metabolite Library | Anti-Prostate Cancer Compound Library | Cancer Stem Cells Compound Library | Coagulation and Anti-coagulation Compound Library | Pain-Related Compound Library | Membrane Protein-targeted Compound Library | Membrane Receptor-targeted Compound Library | Cytokine Inhibitors Library | Cell Death Library | Serine/Threonine Kinase Inhibitor Library | Anti-Ovarian Cancer Compound Library | Multi-Target Compound Library | Bioactive Compound Library Max | Anti-Gastric Cancer Compound Library | MG-132 | Rapamycin | Doxorubicin hydrochloride | Bafilomycin A1 | Tamoxifen | Dimethyl sulfoxide | Y-27632 | LY294002 | Paclitaxel | Dexamethasone | Z-VAD-FMK | Acetylcysteine | Angiotensin II human | 2-Deoxy-D-glucose | Puromycin dihydrochloride | Staurosporine | Actinomycin D | SB-431542 | 5-Fluorouracil | Bortezomib | Deferoxamine mesylate | Oxaliplatin | Trametinib | Sorafenib | Temozolomide | Gemcitabine | Decitabine | Osimertinib | Mdivi-1 | Rotenone 品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物；10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；设有专业的实验中心和严格的质控、验证体系；提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；产品的生物活性多经各国客户实验验证；Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；与世界各大制药公司及知名科研机构建立了长期的合作。