耗材描述
Didymin
产品活性:Didymin 是一种黄酮苷,具有抗氧化和抗癌特性。Didymin 通过抑制神经母细胞瘤中的 N-Myc 和上调 RKIP 来诱导细胞凋亡 (apoptosis)。
产品来源: https://www.medchemexpress.cn/didymin.html
研究领域:Apoptosis
作用靶点:Apoptosis
来源:植物 | 芸香科 | 柑橘属
结构分类:黄酮类 | 二氢黄酮 | 酚类 | 单酚类 | 结构分类
In Vitro: Didymin (1-20 μM; 48 h) inhibits cell proliferation in human non-small-cell lung cancer cells.
Didymin (10-20 μM; 12-48 h) induced apoptosis in A549 and H460 cells, without affecting the cell cycle distribution..
In Vivo: Didymin (6 mg/kg/day; i.p.; daily for 28 days) delays the tumor growth in nude mice.
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