耗材描述
Mosloflavone
产品活性:Mosloflavone 从 Scutellaria baicalensis Georgi 中分离出的类黄酮,具有抗 EV71 活性。Mosloflavone 在病毒感染的初始阶段抑制 VP2 病毒复制和蛋白质表达,并抑制病毒 VP2 衣壳蛋白合成。 Mosloflavone 是有前途的杀菌剂,可抑制铜绿假单胞菌的毒力和生物膜形成。
产品来源: https://www.medchemexpress.cn/mosloflavone.html
研究领域:Anti-infection
作用靶点:Enterovirus | Bacterial
来源:植物 | 菊科 | 百能葳 | 植物 | 唇形科
结构分类:黄酮类 | 黄酮 | 酚类 | 单酚类
In Vitro: Mosloflavone shows promising anti-inflammatory activity via inhibition of TNF-α and IL-1β with IC50 values of 16.4 uM and 6.4 uM, respectively; inhibits TNF-α, IL-1β and iNOS levels in the supernatant of mouse macrophage cell line J774A as a dose-dependent manner, it also can be used as a starting point to discover lead structures for treatment of inflammatory and immunomodulatory diseases.
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