Chloranthalactone B 产品活性：Chloranthalactone B 是一种茚满烷型倍半萜类化合物，是可以从中药 Sarcandra glabra 中分离得到的天然产物。Chloranthalactone B 通过抑制 AP-1 和 p38 MAPK 通路来抑制炎症介质的产生。 产品来源： https://www.medchemexpress.cn/chloranthalactone-b.html 研究领域：Immunology/Inflammation | MAPK/ERK Pathway | Apoptosis 作用靶点：AP-1 | p38 MAPK | NO Synthase | TNF Receptor | COX | Interleukin Related 来源：植物 | 金粟兰科 | 草珊瑚 结构分类：萜类 | 倍半萜 | 结构分类 In Vitro: Chloranthalactone B (6.25-50 µM; 30 min) has anti-inflammatory effects in LPS-stimulated RAW264.7 cells and inhibits NO production. Chloranthalactone B (25 and 50 µM; 30 min) inhibits inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), tumor necrosis factor α (TNF-α), and interleukin-1β (IL-1β) expression in LPS-treated RAW264.7 cells. Chloranthalactone B (25 and 50 µM; RAW264.7 cells) inhibits LPS-induced AP-1 activation in a concentration-dependent manner. Chloranthalactone B (25 and 50 µM; 30 min; RAW264.7 cells) inhibits the phosphorylation of ERK, JNK, and p38 in RAW264.7 cells. 相关产品：Adezmapimod | Resatorvid | Disulfiram | SB 202190 | Polyinosinic-polycytidylic acid | Afatinib | Acetaminophen | T-5224 | Indomethacin | Raleukin | Deucravacitinib | L-NAME hydrochloride | Shikonin | Mifepristone | EIPA | Celecoxib | Doramapimod | Aspirin | Infliximab | Dupilumab | Tocilizumab | Midostaurin | Apilimod | Fisetin | Oxidopamine hydrobromide | L-Arginine | Deferiprone | BI-3406 | SR 11302 品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物；10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；设有专业的实验中心和严格的质控、验证体系；提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；产品的生物活性多经各国客户实验验证；Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；与世界各大制药公司及知名科研机构建立了长期的合作。