Pectic acid 产品活性：Pectic acid (Methyl protopectin) 是一种聚半乳糖醛酸，可诱导垂体肿瘤细胞凋亡 (apoptosis) 和坏死 (necrosis)。Pectic acid 可用于癌症和自身免疫性疾病的研究。 产品来源： https://www.medchemexpress.cn/pectic-acid.html 研究领域：Apoptosis | Metabolic Enzyme/Protease 作用靶点：Apoptosis | Necroptosis | Endogenous Metabolite 来源：植物 | 芸香科 | 柑橘 结构分类：糖类 | 多糖 | 其他类 | 结构分类 In Vitro: Pectic acid (2.5-100 μg/mL, 30 min) stimulates the release of prolactin (PRL) in GH3/B6 cells, without affecting the viability of cells. Pectic acid (100 μg/mL-5 mg/mL, 6-48 h) increases cell death and DNA damage in GH3/B6 cells, detected by MTT assay and AO/EB staining. Pectic acid (100 μg/mL-1 mg/mL, 24 h) induces apoptosis in GH3/B6 cells in a dose-dependent manner. Pectic acid (2.5-5 mg/mL, 24 h) induces necrosis in GH3/B6 cells, confirmed by PI staining. In Vivo: Pectic acid (25 and 100 mg/kg, oral gavage) increases colon length, downregulates disease activity index, histopathological score and proinflammatory cytokine levels in Ulcerative colitis (UC) mice. Pectic acid (6.25 and 12.5 mg/kg, intravenous injection) rescues the reduction in colon length in UC mice. 相关产品：MG-132 | Rapamycin | 3-Methyladenine | Doxorubicin hydrochloride | Bafilomycin A1 | Tamoxifen | Y-27632 | LY294002 | Paclitaxel | Z-VAD-FMK | Acetylcysteine | Angiotensin II human | 2-Deoxy-D-glucose | Staurosporine | Actinomycin D | SB-431542 | 5-Fluorouracil | Bortezomib | Deferoxamine mesylate | Oxaliplatin | Trametinib | Sorafenib | ATP | Retinoic acid | Temozolomide | Gemcitabine | Decitabine | Mdivi-1 | Rotenone | Etoposide 品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物；10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；设有专业的实验中心和严格的质控、验证体系；提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；产品的生物活性多经各国客户实验验证；Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；与世界各大制药公司及知名科研机构建立了长期的合作。