Corynoxine 产品活性：Corynoxine 是一种从 Uncaria rhynchophylla 中分离出的四环羟吲哚生物碱。Corynoxine 是一种天然的自噬增强剂，可通过 Akt/mTOR 途径促进 α-突触核蛋白的清除。 产品来源： https://www.medchemexpress.cn/Corynoxine.html 研究领域：Autophagy 作用靶点：Autophagy 来源：植物 | 茜草科 | 钩藤 结构分类：生物碱 | 吲哚类生物碱 In Vitro: Corynoxine (6.25-25 μM; 6-12 h) increases the expression of LC3-II, an autophagy specific marker, in N2a and SH-SY5Y cells in a dose-dependent manner. Corynoxine (25 μM; 48 h) promotes the degradation of wild type (WT) and mutant (A53T) α-syn in inducible PC12 cells via autophagy induction. In Vivo: Corynoxine (100-100 mg/kg; oral gavage) exhibits prolongation of the thiopental-induced hypnosis in mice. Corynoxine (10-100 μM for 12 h) induces autophagy in drosophila. 相关产品：Natural Product Library Plus | Bioactive Compound Library Plus | Natural Product Library | Anti-Cancer Compound Library | Autophagy Compound Library | Orally Active Compound Library | Traditional Chinese Medicine Active Compound Library | Alkaloids Library | Anti-Cancer Natural Product Library | Plant-Sourced Natural Product Library | Heterocyclic Compound Library | Cell Death Library | Bioactive Compound Library Max | MG-132 | Rapamycin | 3-Methyladenine | Cisplatin | Cycloheximide | Chloroquine | Doxorubicin hydrochloride | Bafilomycin A1 | Tamoxifen | Olaparib | LY294002 | Paclitaxel | Dexamethasone | Laduviglusib | Forskolin | Actinomycin D | Venetoclax | Bortezomib | Deferoxamine mesylate | Trametinib | Sorafenib | Dorsomorphin | Necrostatin-1 | Retinoic acid | Temozolomide | Gemcitabine | Mdivi-1 | Rotenone | Etoposide | Adezmapimod 品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物；10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；设有专业的实验中心和严格的质控、验证体系；提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；产品的生物活性多经各国客户实验验证；Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；与世界各大制药公司及知名科研机构建立了长期的合作。