Dictamine 产品活性：Dictamnine (Dictamine)对人宫颈、结肠癌细胞呈现细胞毒性，还具有抗细菌和抗真菌活性。 产品来源： https://www.medchemexpress.cn/dictamine.html 研究领域：Apoptosis | Anti-infection 作用靶点：Apoptosis | Bacterial | Fungal 来源：植物 | 其他科 结构分类：生物碱 | 喹啉类生物碱 | 结构分类 In Vitro: Dictamine shows antimicrobial activity against Saccharomyces cerevisiae (MIC: 64 μg/mL). Dictamine (2 μg/mL, 24 h) reduces ROS and mitochondrial ROS, and reduces IL-1β, TNF-α expression in HaCaT inflammation model. Dictamine (0-100 μM, 12 h) inhibits cell proliferation, migration and invasion, and induces apoptosis in HCT116 cells, by downregulating HIF-1α and Slug. I. In Vivo: Dictamine (2 μg/mL, 200 μL, applied once daily, for 14 days) reduces skin inflammation and skin swellingin Oxazolone (HY-126360)-induced atopic dermatitis mice model. Dictamine (50 and 100 mg/kg, p.o., three times a week) inhibits tumor growth in a HCT116 xenograft tumor model. Dictamine (1 and 5 mg/kg, 200 μL, applied to the skin) ameliorates chronic itch in 2,4-dinitrofluorobenzene-induced atopic dermatitis mice. 相关产品：Natural Product Library Plus | Bioactive Compound Library Plus | Anti-Infection Compound Library | Apoptosis Compound Library | Immunology/Inflammation Compound Library | Natural Product Library | Anti-Cancer Compound Library | Antifungal Compound Library | Antibacterial Compound Library | Pyroptosis Compound Library | Traditional Chinese Medicine Active Compound Library | Alkaloids Library | Anti-Colorectal Cancer Compound Library | Anti-Cancer Natural Product Library | Anti-inflammatory Traditional Chinese Medicine Active Compound Library | Plant-Sourced Natural Product Library | Human Metabolite Library | Cell Death Library | Bioactive Compound Library Max | MG-132 | Rapamycin | Ferrostatin-1 | Cycloheximide | Doxorubicin hydrochloride | Bafilomycin A1 | Tamoxifen | Dimethyl sulfoxide | Y-27632 | LY294002 | Paclitaxel | Dexamethasone | Z-VAD-FMK | Acetylcysteine | Angiotensin II human | 2-Deoxy-D-glucose | Puromycin dihydrochloride | Staurosporine | Actinomycin D | SB-431542 | 5-Fluorouracil | Bortezomib | Deferoxamine mesylate | Oxaliplatin | Trametinib | Sorafenib | Temozolomide | Gemcitabine | Decitabine | Mdivi-1 品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物；10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；设有专业的实验中心和严格的质控、验证体系；提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；产品的生物活性多经各国客户实验验证；Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；与世界各大制药公司及知名科研机构建立了长期的合作。