Rhoifolin 产品活性：Rhoifolin 是一种黄酮糖苷，可从野洋漆分离。 Rhoifolin 通过增强脂联素分泌、胰岛素受体-β (insulin receptor-β) 的酪氨酸磷酸化和 GLUT4 易位来发挥抗糖尿病作用。Rhoifolin 通过对炎症介质的多层次调控发挥抗炎作用。Rhoifolin 通过 RANKL 诱导的 NF-κB 和 MAPK 途径改善钛颗粒刺激的骨溶解并减弱破骨细胞生成。Rhoifolin 对多种癌细胞系也具有细胞毒性活性。 产品来源： https://www.medchemexpress.cn/rhoifolin.html 研究领域：Protein Tyrosine Kinase/RTK | Membrane Transporter/Ion Channel | NF-κB | MAPK/ERK Pathway | Autophagy 作用靶点：Insulin Receptor | GLUT | NF-κB | p38 MAPK | Autophagy 来源：植物 | 漆树科 | 野洋漆 结构分类：黄酮类 | 黄酮 | 结构分类 In Vitro: Rhoifolin (0-0.1 μM) has cytotoxic activity against different cancer cell lines with 77.0 nM, 60.1 nM, 39.0 nM, 10.7 nM and 10.1 nM in MRC-5, HCT, HepG2, HeLa and Hep2, respectively. In Vivo: Rhoifolin (12, 24, 30, 36, and 40 mg/kg; PO, for 7 days) has radioprotective effect against radiation-induced decrease of blood platelets and cardiac biochemical lesions in whole body irradiated mice. 相关产品：Natural Product Library Plus | Bioactive Compound Library Plus | Immunology/Inflammation Compound Library | MAPK Compound Library | Membrane Transporter/Ion Channel Compound Library | NF-κB Signaling Compound Library | Protein Tyrosine Kinase Compound Library | Stem Cell Signaling Compound Library | Natural Product Library | Anti-Cancer Compound Library | Autophagy Compound Library | Anti-Aging Compound Library | Antioxidant Compound Library | Anti-diabetic Compound Library | Glycoside Compound Library | Lipid Compound Library | Oxygen Sensing Compound Library | Endocrinology Compound Library | Medicine Food Homology Compound Library | Glycolysis Compound Library | Pyroptosis Compound Library | Orally Active Compound Library | Glutamine Metabolism Compound Library | Traditional Chinese Medicine Active Compound Library | Flavonoids Library | Anti-Lung Cancer Compound Library | Anti-Pancreatic Cancer Compound Library | Anti-Cancer Metabolism Compound Library | Neurodegenerative Disease-related Compound Library | Angiogenesis-Related Compound Library | Transcription Factor-Targeted Library | Glucose Metabolism Compound Library | Food-Sourced Compound Library | Anti-Cancer Natural Product Library | Protein-protein Interaction Inhibitor Library | Anti-inflammatory Traditional Chinese Medicine Active Compound Library | Plant-Sourced Natural Product Library | Human Metabolite Library | Osteogenesis Compound Library | Heterocyclic Compound Library | Pain-Related Compound Library | Metabolic Enzyme Compound Library | Membrane Protein-targeted Compound Library | Membrane Receptor-targeted Compound Library | Cell Death Library | Multi-Target Compound Library | Radioprotector Library | Bioactive Compound Library Max | Phorbol 12-myristate 13-acetate | Bortezomib | Insulin (human) | Adezmapimod | BAY 11-7082 | SB 202190 | Insulin(cattle) | TAK-243 | Afatinib | JSH-23 | BAY-876 | Shikonin | Sulfasalazine | Doramapimod | Triptolide | Aspirin | Pyrrolidinedithiocarbamate ammonium | Baicalin | Dihydroartemisinin | Ceritinib | Linsitinib | Oxidopamine hydrobromide | 5-Aminosalicylic Acid | BI-3406 | Parthenolide | CBL0137 hydrochloride | Isoginkgetin | BAY 11-7085 品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物；10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；设有专业的实验中心和严格的质控、验证体系；提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；产品的生物活性多经各国客户实验验证；Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；与世界各大制药公司及知名科研机构建立了长期的合作。