耗材描述
Fargesin
产品活性:Fargesin 是一种从木兰植物中分离出的活性新木脂素,具有抗高血压和抗炎作用。
产品来源: https://www.medchemexpress.cn/fargesin.html
研究领域:Immunology/Inflammation
作用靶点:AP-1
来源:植物 | 木兰科 | 辛夷
结构分类:苯丙素类 | 木脂素 | 结构分类
In Vitro: Fargesin exhibits anti-inflammation effects on THP-1 cells via suppression of PKC pathway including downstream JNK, nuclear factors AP-1 and NF-ĸB.
Fargesin as a potential β₁ adrenergic receptor antagonist protects the hearts against ischemia/reperfusion injury in rats via attenuating oxidative stress and apoptosis.
In Vivo: Fargesin has antihypertensive effect in 2K1C hypertensive rats via inhibiting oxidative stress and promoting NO release.
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