alpha-Asarone 产品活性：alpha-Asarone (α-Asarone) 是菖蒲属中主要的活性物质，具有抗抑郁等功效。 产品来源： https://www.medchemexpress.cn/alpha-Asarone.html 研究领域：Membrane Transporter/Ion Channel | Neuronal Signaling 作用靶点：GABA Receptor 来源：植物 | 天南星科 | 石菖蒲 结构分类：苯丙素类 | 简单苯丙素 | 结构分类 In Vitro: The results indicated that α-asarone significantly attenuated the LPS-stimulated increase in neuroinflammatory responses and suppressed pro-inflammatory cytokine production in BV-2 cells. Mechanistic study revealed that alpha-Asarone (α-Asarone) inhibited the LPS-stimulated activation via regulation of nuclear factor kappa-B by blocking degradation of inhibitor kappa B-alpha signaling in BV-2 microglial cells. In Vivo: The present results reveal that the acute treatment of alpha-Asarone (α-Asarone) elicited biphasic responses on immobility such that the duration of the immobility time is significantly reduced at lower doses (15 and 20 mg/kg, i.p.) but increased at higher doses (50 and 100 mg/kg, i.p.) in the TST. Besides, alpha-Asarone (α-Asarone) at higher doses (50 and 100 mg/kg, i.p.) significantly decreased the spontaneous locomotor activity. 相关产品：Natural Product Library Plus | Drug Repurposing Compound Library Plus | FDA-Approved Drug Library Plus | FDA-Approved Drug Library Mini | Bioactive Compound Library Plus | Membrane Transporter/Ion Channel Compound Library | Neuronal Signaling Compound Library | Natural Product Library | FDA-Approved Drug Library | Drug Repurposing Compound Library | NMPA-Approved Drug Library | Medicine Food Homology Compound Library | Neurotransmitter Receptor Compound Library | Traditional Chinese Medicine Active Compound Library | FDA Approved & Pharmacopeial Drug Library | Anti-Alzheimer's Disease Compound Library | Neuroprotective Compound Library | Anti-Parkinson's Disease Compound Library | Neurodegenerative Disease-related Compound Library | Food-Sourced Compound Library | Antidepressant Compound Library | Plant-Sourced Natural Product Library | GABA Receptor Compound Library | Human Metabolite Library | Off-patent Drug Library | Membrane Protein-targeted Compound Library | Membrane Receptor-targeted Compound Library | FDA-Approved Traditional Chinese Medicine Active Compound Library | Ion Channel Compound Library | Bioactive Compound Library Max | Bicuculline | γ-Aminobutyric acid | Picrotoxin | Aminooxyacetic acid hemihydrochloride | Propofol | Riluzole | Furosemide | Gabazine | Baclofen | Amentoflavone | Vigabatrin | CGP52432 | Flumazenil | Methionine | Jujuboside A | L-Cycloserine | Etiocholanolone | THIP | Topiramate | Broflanilide | Tiagabine hydrochloride | Muscimol | Clomethiazole | (S)-SNAP5114 | Dihydroergotoxine mesylate | Emamectin Benzoate | Ginkgolide A 品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物；10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；设有专业的实验中心和严格的质控、验证体系；提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；产品的生物活性多经各国客户实验验证；Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；与世界各大制药公司及知名科研机构建立了长期的合作。