耗材描述
Kuromanin chloride
产品活性:Kuromanin chloride (Chrysontemin) 来源于桑叶,具有提高血糖浓度、维持脂质代谢平衡以降低肥胖的作用。Kuromanin chloride 还可以抑制 CD38 酶活性。
产品来源: https://www.medchemexpress.cn/Kuromanin-chloride.html
研究领域:Immunology/Inflammation
作用靶点:CD38
来源:植物 | 桑科 | 桑
结构分类:黄酮类 | 花色素类 | 酚类 | 多酚类 | 结构分类
In Vitro: Kuromanin chloride (5 μg/mL) reduces the expression of Ad36 E1A viral gene in 3T3L1 cells infected with 4 MOI of Ad36.
Kuromanin chloride (100 μM, 24 h) protects cerebellar granule neurons from nitric oxide (NO)-induced apoptosis.
Kuromanin chloride (30 and 100 μM, 30 min) inhibits enzymatic activities of CD38, and blocks chronic lymphocytic leukemia (CLL) chemotaxis in CD38+ CLL cells (a fluorimetric assay based on cGDPR generation from NGD).
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