Punicalin 产品活性：Punicalin 是一种可从 Punica granatum 的叶子中分离得到。Punicalin 是一种抗乙型肝炎病毒 (HBV) 活性分子，Punicalin 可诱导细胞焦亡 (pyroptosis)。Punicalin 是一种碳酸酐酶 (Carbonic anhydrase) 抑制剂。Punicalin 可阻断 S-glycoprotein 与 ACE2 受体的结合。Pnuicalin 有抗炎、抗氧化和抗病毒活性。 产品来源： https://www.medchemexpress.cn/punicalin.html 研究领域：Anti-infection | Immunology/Inflammation | Apoptosis | Metabolic Enzyme/Protease 作用靶点：HBV | Pyroptosis | Carbonic Anhydrase 来源：植物 | 石榴科 | 石榴 结构分类：酚类 | 多酚类 | 结构分类 In Vitro: Punicalin (0-100 μM, 24 h) improves LPS/ ATP-induced pyroptosis in mouse mononuclear macrophage J774A by inhibiting ROS/NLRP3 pathway. Punicalin (10, 20 μM, 24 h) alleviates OGD/R-induced cell damage through TGF-β-mediated neuroblastoma SH-SY5Y oxidative stress and cell cycle. In Vivo: Punicalin (5 mg/kg, subcutaneous injection) has an obvious anti-inflammatory effect on carrageenan (HY-125474)-induced metatarsal edema in rats. Punicalin (10 mg/kg, intraperitoneal injection) alleviates LPS (HY-D1056)-induced acute lung injury in mice by inhibiting the production of inflammatory cytokines and MAPK/ NF-κB signaling. 相关产品：Covalent Screening Library Plus | Natural Product Library Plus | Bioactive Compound Library Plus | Anti-Infection Compound Library | Apoptosis Compound Library | Immunology/Inflammation Compound Library | Metabolism/Protease Compound Library | Natural Product Library | Antiviral Compound Library | Anti-Aging Compound Library | Covalent Screening Library | Antioxidant Compound Library | Macrocyclic Compound Library | Oxygen Sensing Compound Library | Phenols Library | Traditional Chinese Medicine Active Compound Library | Food-Sourced Compound Library | Antiviral Traditional Chinese Medicine Active Compound Library | Anti-inflammatory Traditional Chinese Medicine Active Compound Library | Plant-Sourced Natural Product Library | Metabolic Enzyme Compound Library | Cell Death Library | Multi-Target Compound Library | Radioprotector Library | Bioactive Compound Library Max | Cisplatin | Doxorubicin hydrochloride | Nicotinamide | Disulfiram | 2-Bromohexadecanoic acid | Indisulam | Punicalagin | LDC7559 | OSS_128167 | Lamivudine | Acetazolamide | RO8191 | Tenofovir | U-104 | Estradiol benzoate | Sodium metatungstate | Polyphyllin VI | Ac-FLTD-CMK | Vesatolimod | NLRP3/AIM2-IN-3 | Isochlorogenic acid A | Entecavir monohydrate | Catalpol | RG7834 | Thiamine hydrochloride | Selgantolimod | Ethoxzolamide | 4,5-Dicaffeoylquinic acid | Bulevirtide 品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物；10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；设有专业的实验中心和严格的质控、验证体系；提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；产品的生物活性多经各国客户实验验证；Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；与世界各大制药公司及知名科研机构建立了长期的合作。