耗材描述
Ginsenoside F1
产品活性:Ginsenoside F1 是 Ginsenoside Rg1 的酶促修饰衍生物,Ginsenoside F1 竞争性抑制 CYP3A4,对 CYP2D6 具有较弱的抑制作用。
产品来源: https://www.medchemexpress.cn/Ginsenoside-F1.html
研究领域:Metabolic Enzyme/Protease
作用靶点:Cytochrome P450 | Endogenous Metabolite
来源:植物 | 五加科 | 人参
结构分类:萜类 | 三萜
In Vitro: Ginsenoside F1 has been shown to flaunt anticancer, anti-aging, and antioxidant effects and has demonstrated competitive inhibition of CYP3A4 activity and weaker inhibition of CYP2D6 activity. The cell viabilities are 68% at the highest concentration of ginsenoside F1 (200 μM) in MTT assays.
In Vivo: ApoE-/- mice are fed a high fat diet and orally treated with Ginsenoside F1 (50 mg/kg/day) for 8 weeks. Ginsenoside F1 treated mice significantly reduce the lesion size compared with model group mice.
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