耗材描述
Mogroside V
产品活性:Mogroside V 是中药罗汉果的主要活性成分。Mogroside V 能降低细胞内 ROS 水平,增强线粒体功能。Mogroside V 具有抗氧化、抗糖尿病和抗癌等作用,可用于糖尿病疾病的研究。
产品来源: https://www.medchemexpress.cn/mogroside-v.html
研究领域:Immunology/Inflammation | NF-κB | Metabolic Enzyme/Protease
作用靶点:Reactive Oxygen Species
来源:植物 | 葫芦科 | 罗汉果
结构分类:萜类 | 三萜 | 结构分类
In Vitro: Mogroside V (20 μM, 40 h) reducs the ROS levels in in vitro maturation (IVM) oocytes.
Mogroside V (20 μM, 40 h) can enhance mitochondrial function in oocytes.
Mogroside V (1-250 μM, 24 h) promots apoptosis and cell cycle arrest of pancreatic cancer cells (PANC-1 cells) and may be mediated through regulating the STAT3 signaling pathway.
In Vivo: Mogroside V (100 mg/kg for Oral administration) transforms to 26 metabolites by the process of dehydrogenation, deoxidation, oxidation and isomerization in type 2 diabetes (T2D) model rats.
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