Obacunone 产品活性：Obacunone 是一种高度氧化的三萜类柠檬苦素，能够从柑橘属植物中分离得到的。Obacunone 通过诱导凋亡发挥抗癌作用。Obacunone 还可防止视网膜色素上皮 (RPE) 细胞受到紫外线 (UV) 辐射 (UVR) 诱导的氧化损伤。 产品来源： https://www.medchemexpress.cn/obacunone.html 研究领域：Apoptosis 作用靶点：Apoptosis 来源：植物 | 芸香科 | 柑橘属 结构分类：萜类 | 三萜 | 结构分类 In Vitro: Obacunone (1-50 μM; 48 h) effectively inhibits UVR-induced cytotoxicity.Obacunone (25 μM; 1 h+12 h) improves UVR-induced oxidative damage in ARPE-19 cells and inhibits reactive oxygen species accumulation, mitochondrial depolarization, lipid peroxidation, and single-stranded DNA accumulation in human ARPE-19 cells.Obacunone (25 μM; 1 h+12 h) slows UVR-induced apoptosis in human ARPE-19 cells and murine RPE cells. In Vivo: Obacunone (10 mg/kg; ip; single dose) inhibits Bleomycin (HY-108345)-induced lung inflammation and fibrosis in B6 mice. 相关产品：Covalent Screening Library Plus | Natural Product Library Plus | Bioactive Compound Library Plus | Apoptosis Compound Library | Natural Product Library | Anti-Cancer Compound Library | Covalent Screening Library | Medicine Food Homology Compound Library | Terpenoids Library | Traditional Chinese Medicine Active Compound Library | Food-Sourced Compound Library | Anti-Cancer Natural Product Library | Plant-Sourced Natural Product Library | Cysteine Targeted Covalent Library | Cell Death Library | Bioactive Compound Library Max | MG-132 | Doxorubicin hydrochloride | Bafilomycin A1 | Tamoxifen | Y-27632 | LY294002 | Paclitaxel | Z-VAD-FMK | Acetylcysteine | Angiotensin II human | 2-Deoxy-D-glucose | Staurosporine | Actinomycin D | SB-431542 | 5-Fluorouracil | Bortezomib | Deferoxamine mesylate | Oxaliplatin | Trametinib | Sorafenib | Temozolomide | Gemcitabine | Decitabine | Mdivi-1 | Rotenone | Etoposide | Elesclomol | Ruxolitinib | Monomethyl auristatin E | DAPT 品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物；10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；设有专业的实验中心和严格的质控、验证体系；提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；产品的生物活性多经各国客户实验验证；Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；与世界各大制药公司及知名科研机构建立了长期的合作。