p-Coumaric acid 产品活性：p-Coumaric acid (trans-4-Hydroxycinnamic acid) 是一种具有口服活性的肉桂酸的异构体。p-Coumaric acid 可抑制细胞增殖，促进细胞凋亡 (apoptosis)。p-Coumaric acid 具有抗菌 (antibacterial)、抗炎、抗氧化和抗肿瘤活性。 产品来源： https://www.medchemexpress.cn/p-Coumaric_acid.html 研究领域：Metabolic Enzyme/Protease | Anti-infection | Apoptosis 作用靶点：Endogenous Metabolite | Bacterial | Apoptosis 来源：植物 | 其他科 结构分类：苯丙素类 | 简单苯丙素 | 酚类 | 单酚类 | 结构分类 In Vitro: p-Coumaric acid (1 or 3 μg/mL, 24, 48, 72 h) can significantly inhibit the proliferation of human and mouse melanoma cells in vitro and promote cell apoptosis. p-Coumaric acid (10-80 μg/mL) shows antibacterial activity against both gram-negative and Gram-positive bacteria, and MIC values for Escherichia coli, Streptococcus dysenteriae and Salmonella typhimurium are 80, 10 and 20 μg/ml. In Vivo: p-Coumaric acid (50, 100, 200 mg/kg, suspended in 0.5% carboxymethyl cellulose (CMC), was administered daily via gastric cannula for 15 weeks) It has a protective effect on colon pretumor induced by 1,2 dimethylhydrazine (DMH) in rats. p-Coumaric acid (15, 100 mg/kg, oral) alleviates nephrotoxicity induced by Doxorubicin (HY-15142A) in rats by inhibiting oxidative stress, inflammation and apoptosis. 相关产品：Natural Product Library Plus | Bioactive Compound Library Plus | Anti-Infection Compound Library | Apoptosis Compound Library | Immunology/Inflammation Compound Library | Metabolism/Protease Compound Library | Natural Product Library | Anti-Cancer Compound Library | Human Endogenous Metabolite Compound Library | Fragment Library | Anti-Aging Compound Library | Antioxidant Compound Library | Oxygen Sensing Compound Library | Antibacterial Compound Library | Medicine Food Homology Compound Library | Phenols Library | Orally Active Compound Library | Traditional Chinese Medicine Active Compound Library | FDA Approved & Pharmacopeial Drug Library | Microbial Metabolite Library | Food-Sourced Compound Library | Anti-Cancer Natural Product Library | Anti-inflammatory Traditional Chinese Medicine Active Compound Library | Plant-Sourced Natural Product Library | Human Metabolite Library | Animal-Sourced Natural Product Library | Highly Selective Inhibitors Library | Highly Selective Activators Library | Cell Death Library | Multi-Target Compound Library | Radioprotector Library | Bioactive Compound Library Max | MG-132 | Rapamycin | 3-Methyladenine | Doxorubicin hydrochloride | Bafilomycin A1 | Tamoxifen | Dimethyl sulfoxide | Y-27632 | LY294002 | Paclitaxel | Dexamethasone | Z-VAD-FMK | Acetylcysteine | Angiotensin II human | 2-Deoxy-D-glucose | Puromycin dihydrochloride | Staurosporine | Actinomycin D | SB-431542 | 5-Fluorouracil | Bortezomib | Deferoxamine mesylate | Oxaliplatin | Trametinib | Sorafenib | ATP | Retinoic acid | Temozolomide | Gemcitabine | Decitabine 品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物；10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；设有专业的实验中心和严格的质控、验证体系；提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；产品的生物活性多经各国客户实验验证；Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；与世界各大制药公司及知名科研机构建立了长期的合作。