耗材描述
Pectolinarin
产品活性:Pectolinarin 具有抗炎活性。Pectolinarin 抑制 IL-6 和 IL-8 分泌以及 PGE2 和 NO 产生。Pectolinarin 可通过抑制 PI3K/Akt 途径来抑制细胞增殖和炎症反应并诱导凋亡 (apoptosis)。
产品来源: https://www.medchemexpress.cn/pectolinarin.html
研究领域:Immunology/Inflammation | GPCR/G Protein | Apoptosis
作用靶点:Interleukin Related | Prostaglandin Receptor | Apoptosis
来源:植物 | 豆科 | 狭叶羽扇豆 | 植物 | 菊科
结构分类:黄酮类 | 黄酮 | 酚类 | 单酚类 | 结构分类
In Vitro: Pectolinarin increases Bax level, and decreases Bcl-2 level in rheumatoid arthritis fibroblast-like synoviocytes (RA-FLSs). Pectolinarin inactivates the PI3K/Akt pathway in RA-FLSs.
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