Irisflorentin 产品活性：Irisflorentin 是一种天然存在的异黄酮，是射干中丰富的一种活性成分。Irisflorentin 显着降低了诱导型一氧化氮合酶 (iNOS) 的转录和翻译水平以及 NO 产生。 产品来源： https://www.medchemexpress.cn/irisflorentin.html 研究领域：Immunology/Inflammation 作用靶点：NO Synthase 来源：植物 | 鸢尾科 | 射干 结构分类：黄酮类 | 异黄酮 In Vitro: Irisflorentin does not affect the LPS-stimulated RAW 264.7 macrophages viability up to a concentration of 40 μM. Irisflorentin (10-40 μM) inhibits the LPS-induced production of NO in a concentration-dependent manner without affecting the iNOS activity in RAW 264.7 macrophages. Irisflorentin (10-40 μM) concentration dependently inhibits the LPS (10 ng/mL)-induced increase in iNOS mRNA expression in LPS stimulated RAW 264.7 macrophages. Irisflorentin (10-40 μM) concentration-dependently suppresses the production of TNF-α, IL-1β and IL-6 in LPS stimulated RAW 264.7 macrophages. Irisflorentin (10-40 μM) concentration dependently inhibits the LPS (10 ng/mL)-induced increase in iNOS protein levels. Irisflorentin (10-40 μM) concentration-dependently suppresses LPS-induced p38 and ERK1/2 phosphorylation in a concentration-dependent manner, but slightly affects JNK phosphorylation. 相关产品：Natural Product Library Plus | Bioactive Compound Library Plus | Immunology/Inflammation Compound Library | Natural Product Library | Anti-Aging Compound Library | Medicine Food Homology Compound Library | Pyroptosis Compound Library | Traditional Chinese Medicine Active Compound Library | FDA Approved & Pharmacopeial Drug Library | Flavonoids Library | Neuroprotective Compound Library | Angiogenesis-Related Compound Library | Anti-inflammatory Traditional Chinese Medicine Active Compound Library | Plant-Sourced Natural Product Library | Anti-Pulmonary Fibrosis Compound Library | Mitochondrial Protection Compound Library | Metabolic Enzyme Compound Library | Membrane Protein-targeted Compound Library | Bioactive Compound Library Max | L-NAME hydrochloride | Mifepristone | Midostaurin | L-Arginine | DMPO | S-Nitroso-N-acetyl-DL-penicillamine | 1400W Dihydrochloride | DETA NONOate | Human serum albumin | Isoquercetin | Ethacrynic acid | Methylene Blue | Fucoxanthin | L-NMMA acetate | Chondroitin sulfate | Tetrahydrobiopterin | PRE-084 hydrochloride | 2,4-Diamino-6-hydroxypyrimidine | L-NIL | Aminoguanidine hydrochloride | Lipoamide | Asymmetric dimethylarginine | Carboxy-PTIO potassium | Avanafil | Prim-O-glucosylcimifugin | Agmatine sulfate | Ginsenoside C-K | 6-Biopterin | Tryptanthrin 品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物；10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；设有专业的实验中心和严格的质控、验证体系；提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；产品的生物活性多经各国客户实验验证；Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；与世界各大制药公司及知名科研机构建立了长期的合作。