耗材描述
嘌呤霉素无菌溶液
MCE Puromycin, Sterile 来源于白黑链霉菌(Streptomyces alboniger),是一种氨基糖苷类抗生素,可以通过抑制蛋白质合成从而杀死多数革兰氏阳性菌及各种动物或昆虫细胞,在某种特殊情况下也可有效作用于大肠杆菌。
产品来源: https://www.medchemexpress.cn/inhibitor-kit/puromycin-sterile.html
Description & Advantages: Puromycin is an aminonucleoside antibiotic produced by Streptomyces alboniger. It inhibits protein synthesis by disrupting peptide transfer on ribosomes, causing premature chain termination during translation. It can kill most gram-positive bacteria and various animal or insect cells.
Resistance to Puromycin is conferred by the puromycin N-acetyl-transferase gene (pac) from Streptomyces alboniger. Therefore, Puromycin is a popular and effective antibiotic for selecting vectors bearing the pac gene in mammalian cell lines and E. coli.
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