耗材描述
G418 选择性抗生素无菌溶液
MCE G418 Selective Antibiotic, Sterile 是一种氨基糖苷类抗生素,主要通过影响 80S 核糖体的功能来干扰蛋白质的合成,对细菌、酵母、高等植物、哺乳动物细胞等均有毒性。
产品来源: https://www.medchemexpress.cn/inhibitor-kit/g418-selective-antibiotic-sterile.html
Description & Advantages: G418 selective antibiotic is an aminoglycoside antibiotic produced by Micromonospora rhodorangea. It acts by binding to the 80S subunit of the bacterial ribosome, thus inhibiting protein synthesis in both prokaryotic and eukaryotic cells.
Resistance to G418 selective antibiotic is conferred by the E. coli APH (3) I and APH (3) II resistance genes. The gene becomes APH (3) II on Tn5 and APH (3) I on Tn601. Therefore, G-418 selective antibiotic can be used to select and maintain prokaryotic or eukaryotic cells carrying the G418 resistance gene.
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