耗材描述
潮霉素 B 无菌溶液
MCE Hygromycin B, Sterile 是一种氨基糖苷类抗生素,主要通过干扰 70S 核糖体易位和诱导对 mRNA 模板的错读而抑制细胞蛋白质的正常合成,从而导致细菌、真菌和哺乳动物细胞死亡。
产品来源: https://www.medchemexpress.cn/inhibitor-kit/hygromycin-b-sterile.html
Description & Advantages: Hygromycin B is an aminoglycosidic antibiotic purified from Streptomyces hygroscopicus. It acts by binding to the 70S subunit of the bacterial ribosome and inhibiting protein synthesis, leading to the death of bacteria, fungi and mammalian cells.
Resistance to Hygromycin B is conferred by the E. coli hygromycin resistance gene (hyg or hph). Therefore, Hygromycin B can be used to select and maintain prokaryotic and eukaryotic cells transfected with the hygromycin resistance gene. Low purity hygromycin can cause different toxic effects, so it is crucial to grasp its purity in the experiment.
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