(±)-α-Tocopherol nicotinate 产品活性：(±)-α-Tocopherol nicotinate，维生素 E-烟酸酯，是一种具有口服活性的脂溶性抗氧化剂，能够防止细胞膜脂质过氧化。(±)-α-Tocopherol nicotinate 在血液中可水解为 α -生育酚和烟酸，可用于相关血管疾病的研究。 产品来源： https://www.medchemexpress.cn/racemic-α-tocopherol-nicotinate.html 研究领域：Immunology/Inflammation | NF-κB | Metabolic Enzyme/Protease 作用靶点：Reactive Oxygen Species | Endogenous Metabolite 结构分类：生物碱 | 吡啶类生物碱 | 结构分类 In Vitro: (±)-α-Tocopherol nicotinate can help slow the progression of microangiopathy in type 2 diabetics by reducing lipid peroxidation stress in the red blood cell membrane, improving blood rheology and red blood cell deformability. (±)-α-Tocopherol nicotinate (Vitamin E) (2 μg/mL, 24 h) increases the proportion of CD4+CD8-T cells in thymocytes by pretreating the thymic epithelial cell line IT45-R1 and then incubating it with immature T cells. In Vivo: (±)-α-Tocopherol nicotinate (Vitamin E) (in animal feedings, 50 mg/kg or 585 mg/kg, 7 weeks) significantly increases the proportion of CD4+CD8- T cells and the expression of ICAM-1 in thymic epithelial cells (TECs) isolated of male Fisher rats at high dose concentrations of 585 mg/kg compared to low dose treatment of 50 mg/kg. 相关产品：Natural Product Library Plus | Bioactive Compound Library Plus | Immunology/Inflammation Compound Library | Metabolism/Protease Compound Library | NF-κB Signaling Compound Library | Stem Cell Signaling Compound Library | Natural Product Library | Anti-Aging Compound Library | Antioxidant Compound Library | Anti-diabetic Compound Library | Oxygen Sensing Compound Library | Anti-Cardiovascular Disease Compound Library | Ferroptosis Compound Library | Pyroptosis Compound Library | Orally Active Compound Library | Alkaloids Library | Mitochondria-Targeted Compound Library | Heterocyclic Compound Library | Metabolic Enzyme Compound Library | Radioprotector Library | Mitophagy Compound Library | Bioactive Compound Library Max | Rapamycin | 3-Methyladenine | Acetylcysteine | H2DCFDA | 5-Fluorouracil | Deferoxamine mesylate | MitoSOX Red | ATP | Retinoic acid | Elesclomol | Hydrocortisone | Estradiol | Quercetin | Nicotinamide | Prostaglandin E2 | AICAR | Palmitic acid | Docetaxel | Isoprenaline hydrochloride | L-Ascorbic acid | Cytarabine | Mito-TEMPO | Melatonin | Calcitriol | Capsaicin | Arachidonic acid | Valproic acid | Oleic acid | β-Nicotinamide mononucleotide | Acetaminophen 品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物；10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；设有专业的实验中心和严格的质控、验证体系；提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；产品的生物活性多经各国客户实验验证；Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；与世界各大制药公司及知名科研机构建立了长期的合作。