耗材描述
Octanoic acid
产品活性:Octanoic acid (Caprylic acid) 是一种油性液体,带有些许腐臭味,能用于酯类香料和染料的生产。Octanoic acid 也是一种震颤抑制剂。
产品来源: https://www.medchemexpress.cn/1-Heptanecarboxylic_acid.html
研究领域:Metabolic Enzyme/Protease
作用靶点:Endogenous Metabolite
结构分类:酮、醛、酸 | 结构分类
In Vitro: Octanoic acid (0-0.5 mM, 0.5 h) potentiates glucose-stimulated insulin secretion (GSIS) in MIN6 cells, via Olfr15 though the PLC-IP3 pathway.
Octanoic acid (0-10 mM, 48 h) induces neurite outgrowth in PC12 cells, and activates p38 MAPK and ERK pathways.
In Vivo: Octanoic acid (1500 mg/kg, i.p.) inhibits harmaline tremor in mouse model of essential tremor.
Octanoic acid (150 mg/kg, oral gavage) shows protective effects in the mouse model of PD induced by MPTP (HY-15608).
Octanoic acid (1.3 mg, p.o.) promotes branched-chain amino acid (BCAA) catabolism in rats by activating BCKDC via decreasing the bound form of BCKDH kinase (BDK).
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