Maytansinol 产品活性：Maytansinol (Ansamitocin P-0) 是美登素的一种衍生物。Maytansinol 可抑制微管蛋白 (tublin) 聚合，诱导细胞凋亡 (apoptosis)。Maytansinol 有抗肿瘤活性。Maytansinol 可用于抗癌药物的研究。 产品来源： https://www.medchemexpress.cn/Maytansinol.html 研究领域：Cell Cycle/DNA Damage | Cytoskeleton | Antibody-drug Conjugate/ADC Related | Apoptosis 作用靶点：Microtubule/Tubulin | ADC Cytotoxin | Apoptosis 结构分类：生物碱 | 其他类生物碱 In Vitro: Maytansinol (0.09-0.75 nM, 24 h) decreases the growth and survival of HCT116 cells in a dose-dependent manner . In Vivo: Maytansinol (2 μM, 10 μM, add to food, 1-2 h) can depolymerize microtubules in Drosophila. Maytansinol (0.5-2 μM, add to food, 10 days) decreases the survival rate of wild-type and p53 mutant larvae. Maytansinol (1 or 2 μM, add to food, 24-26 h) can induce apoptosis of wild-type Drosophila cells. 相关产品：Covalent Screening Library Plus | Natural Product Library Plus | Bioactive Compound Library Plus | Apoptosis Compound Library | Cell Cycle/DNA Damage Compound Library | Natural Product Library | Toxins for Antibody-Drug Conjugate Research Library | Anti-Cancer Compound Library | Anti-Aging Compound Library | Covalent Screening Library | Cytoskeleton Compound Library | Alkaloids Library | Anti-Lung Cancer Compound Library | Microbial Metabolite Library | Anti-Cancer Natural Product Library | Protein-protein Interaction Inhibitor Library | Cell Death Library | Bioactive Compound Library Max | MG-132 | Doxorubicin hydrochloride | Bafilomycin A1 | Tamoxifen | Y-27632 | LY294002 | Paclitaxel | Dexamethasone | Z-VAD-FMK | Acetylcysteine | Angiotensin II human | 2-Deoxy-D-glucose | Staurosporine | Actinomycin D | SB-431542 | 5-Fluorouracil | Bortezomib | Deferoxamine mesylate | Oxaliplatin | Trametinib | Sorafenib | Temozolomide | Gemcitabine | Decitabine | Mdivi-1 | Rotenone | Etoposide | Elesclomol | Ruxolitinib | Monomethyl auristatin E 品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物；10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；设有专业的实验中心和严格的质控、验证体系；提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；产品的生物活性多经各国客户实验验证；Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；与世界各大制药公司及知名科研机构建立了长期的合作。