Atosiban 产品活性：Atosiban (RW22164; RWJ22164) 是一种九肽，竞争性的加压素/催产素受体 (vasopressin/oxytocin receptor) 拮抗剂，也是一种脱氨基催产素类似物。Atosiban 是一种主要的宫缩抑制剂，可用于自发早产的研究。 产品来源： https://www.medchemexpress.cn/Atosiban.html 研究领域：GPCR/G Protein 作用靶点：Oxytocin Receptor | Vasopressin Receptor In Vitro: Atosiban inhibits the oxytocin-mediated release of IP3 from the myometrial cell membrane. There is reduced release of intracellular, stored calcium from the sacroplasmic reticulum of myometrial cells, and reduced influx of Ca2+ from the extracellular space through voltage gated channels. In addition, Atosiban suppresses oxytocin-mediated release of PGE and PGF from the decidua. In Vivo: The posterior pituitary hormones, oxytocin and arginine vasopressin, differ in structure by only two amino acids, and Atosiban influences physiological effects of arginine vasopressin on the feto-maternal cardiovascular and renal systems. In late-gestation sheep, the administration of Atosiban for 1 hour fails to induce fetomaternal cardiovascular changes. Atosiban blocks the activation of oxytocin-receptor-expressing neurons in the parabrachial nucleus of mice. 相关产品：Drug Repurposing Compound Library Plus | FDA-Approved Drug Library Plus | Bioactive Compound Library Plus | Macrocyclic Compound Library | Peptide Library | Oxytocin acetate | Conivaptan hydrochloride | Argipressin | L-368,899 hydrochloride | Tolvaptan | Atosiban acetate | LIT-001 | Carbetocin | L-371,257 | Lixivaptan | Mozavaptan hydrochloride | SR 49059 | SRX246 | Felypressin acetate | (Thr4,Gly7)-Oxytocin | Fedovapagon | Terlipressin diacetate | Retosiban | Balovaptan | D[LEU4,LYS8]-VP TFA | TASP0390325 | Fuscoside | Nelivaptan | SKF 100398 | WAY-151932 | Cligosiban | RG7713 品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物；10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；设有专业的实验中心和严格的质控、验证体系；提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；产品的生物活性多经各国客户实验验证；Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；与世界各大制药公司及知名科研机构建立了长期的合作。