Crocetin disodium 产品活性：Crocetin (Transcrocetin) disodium 从藏红花 (Crocus sativus L.) 中提取的，是一种高亲和力的 NMDA 受体拮抗剂。 产品来源： https://www.medchemexpress.cn/Transcrocetinate_disodium.html 研究领域：Membrane Transporter/Ion Channel | Neuronal Signaling 作用靶点：iGluR 来源：植物 | 鸢尾 | 藏红花 结构分类：萜类 | 二萜 | 结构分类 In Vitro: Crocetin (Transcrocetin, trans-Crocetin) disodium, a saffron metabolite originating from the crocin apocarotenoids, has been shown to exert strong NMDA receptor affinity and is thought to be responsible for the CNS activity of saffron.To ensure unchanged viability of Caco-2 cells throughout the transport experiments, cellular mitochondrial dehydrogenase activity of Caco-2 cells is measured by MTT assay after a 24 h incubation period with the test compounds: Hydroalcoholic saffron extract saffron extract (SE, 0.5-1 mg/mL) and crocin-1 (250-1000 µM) reveal no negative significant changes in cellular viability. Crocetin disodium at 10 µM level does not change viability while higher concentrations (40-160 µM) reduces significantly cellular viability. 相关产品：Natural Product Library Plus | Bioactive Compound Library Plus | Membrane Transporter/Ion Channel Compound Library | Neuronal Signaling Compound Library | Natural Product Library | Anti-Cancer Compound Library | Medicine Food Homology Compound Library | Terpenoids Library | Neurotransmitter Receptor Compound Library | Traditional Chinese Medicine Active Compound Library | Anti-Alzheimer's Disease Compound Library | Neuroprotective Compound Library | Anti-Parkinson's Disease Compound Library | Neurodegenerative Disease-related Compound Library | Food-Sourced Compound Library | Anti-Cancer Natural Product Library | Antidepressant Compound Library | Plant-Sourced Natural Product Library | Human Metabolite Library | Membrane Protein-targeted Compound Library | Membrane Receptor-targeted Compound Library | Ion Channel Compound Library | Bioactive Compound Library Max | Corticosterone | Dizocilpine maleate | D-AP5 | NMDA | L-Glutamic acid | Evans Blue | CNQX | Kynurenic acid | Glycine | L-Phenylalanine | NBQX | Quinolinic acid | Cycloleucine | Ifenprodil tartrate | Memantine hydrochloride | D-Cycloserine | DNQX | Ro 25-6981 Maleate | (-)-Huperzine A | Naspm trihydrochloride | Ibotenic acid | 24-Hydroxycholesterol | Crocetin | Decanoic acid | Bupivacaine | Topiramate | Tacrine hydrochloride 品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物；10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；设有专业的实验中心和严格的质控、验证体系；提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；产品的生物活性多经各国客户实验验证；Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；与世界各大制药公司及知名科研机构建立了长期的合作。