YPLP 产品活性：YPLP 是一种酵母衍生肽 Tyr-Pro-Leu-Pro，通过 Nrf2- 和 AMP 激活蛋白激酶 (AMPK) 通路发挥抗疲劳机制活性。YPLP 具有口服活性。 产品来源： https://www.medchemexpress.cn/yplp.html 研究领域：NF-κB | PI3K/Akt/mTOR | Epigenetics 作用靶点：Keap1-Nrf2 | AMPK In Vivo: YPLP (10-50 mg/kg, i.g. for 4 weeks) alleviates exhaustive exercise caused oxidative damage by decreasing lipid oxidation and increasing antioxidant enzyme activities in muscle tissues through Nrf2/Keap1 pathway. YPLP (10-50 mg/kg, i.g. for 4 weeks) improves ATP levels and energy metabolism through phosphorylation of AMPK and promotion of AMPK proteins in fatigue ICR mice. YPLP (10-50 mg/kg, i.g. for 4 weeks) regulates expressions of differential abundance proteins (DAPs), participates in the protein biosynthesis/degradation, muscle dynamics, and nuclear transport process to regulate muscle function in fatigue mice. 相关产品：Doxorubicin hydrochloride | ML385 | Dorsomorphin | Metformin | AICAR | Resveratrol | Curcumin | 4-Octyl itaconate | Sulforaphane | Luteolin | TBHQ | Dimethyl fumarate | Omaveloxolone | A-769662 | Bardoxolone methyl | MK8722 | KI696 | Bempedoic acid | Brusatol | Ezetimibe | GSK-690693 | L-Methionine | Ergothioneine | BAY-3827 | Aldometanib | Oltipraz 品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物；10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；设有专业的实验中心和严格的质控、验证体系；提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；产品的生物活性多经各国客户实验验证；Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；与世界各大制药公司及知名科研机构建立了长期的合作。