耗材描述
Podofilox
产品活性:Podofilox (Podophyllotoxin) 是微管组装和DNA拓扑异构酶II抑制剂。
产品来源: https://www.medchemexpress.cn/Podophyllotoxin.html
研究领域:Cell Cycle/DNA Damage | Cytoskeleton
作用靶点:Microtubule/Tubulin
来源:植物 | 小檗科 | 八角莲
结构分类:苯丙素类 | 木脂素 | 结构分类
In Vitro: Podophyllotoxin, a kind of non-alkaloid toxin lignan extracted from the roots and rhizomes of Podophyllum plant, has been shown to inhibit the growth of various carcinoma cells. Podophyllotoxin is a natural product that inhibits the polymerization of tubulin and has served as a prototype for the development of diverse antitumor agents in clinical use.
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