Hesperidin 产品活性：Hesperidin (Hesperetin 7-rutinoside) 是一种广泛存在于柑橘类水果中黄烷酮糖苷。Hesperidin 具有多种生物学特性，例如减少炎症介质并发挥重要的抗氧化作用。Hesperidin 还表现出抗肿瘤和抗过敏活性。 产品来源： https://www.medchemexpress.cn/Hesperidin.html 研究领域：Apoptosis | Autophagy | Metabolic Enzyme/Protease | Immunology/Inflammation | NF-κB 作用靶点：Apoptosis | Autophagy | Reactive Oxygen Species | Endogenous Metabolite 来源：植物 | 芸香科 | 柑橘属 结构分类：黄酮类 | 二氢黄酮 | 结构分类 In Vitro: Hesperidin (5-200 μM; 24-72 h) induces potent cytotoxic effects in human osteosarcoma MG-63 cells. Hesperidin (5-150 μM; 48 h) induces early and late apoptosis in MG-63 cells. Hesperidin (10-30 μM) inhibits the activity of COX-2 and iNOS in a dose dependent manner in RAW 264.7 cells activated with LPS. Hesperidin (0.1 μg/mL; 2 h) decreases the formation of MDA and intracellular ROS, including chondrocyte apoptosis. In Vivo: Hesperidin (5-80 mg/kg; 2 weeks) significantly suppresses MG-63 tumor growth in mice. Hesperidin (200 mg/kg; once daily for 28 d) markedly attenuates cartilage destruction and reduces IL-1β and TNF-α levels in a surgically-induced osteoarthritis (OA) rats. 相关产品：Natural Product Library Plus | Drug Repurposing Compound Library Plus | FDA-Approved Drug Library Plus | FDA-Approved Drug Library Mini | Bioactive Compound Library Plus | Apoptosis Compound Library | Immunology/Inflammation Compound Library | Metabolism/Protease Compound Library | NF-κB Signaling Compound Library | Stem Cell Signaling Compound Library | Natural Product Library | FDA-Approved Drug Library | Anti-Cancer Compound Library | Antiviral Compound Library | Autophagy Compound Library | Anti-Aging Compound Library | Drug Repurposing Compound Library | Antioxidant Compound Library | Glycoside Compound Library | Lipid Compound Library | Oxygen Sensing Compound Library | Ferroptosis Compound Library | Anti-COVID-19 Compound Library | NMPA-Approved Drug Library | Medicine Food Homology Compound Library | Pyroptosis Compound Library | Orally Active Compound Library | Traditional Chinese Medicine Active Compound Library | FDA Approved & Pharmacopeial Drug Library | Flavonoids Library | Mitochondria-Targeted Compound Library | Food Additive Library | Food-Sourced Compound Library | Anti-Cancer Natural Product Library | Anti-inflammatory Traditional Chinese Medicine Active Compound Library | Plant-Sourced Natural Product Library | FDA-Approved Anticancer Drug Library | Human Metabolite Library | Anti-Pulmonary Fibrosis Compound Library | Anti-Aging Natural Product Library | Heterocyclic Compound Library | Off-patent Drug Library | Metabolic Enzyme Compound Library | Cell Death Library | FDA-Approved Traditional Chinese Medicine Active Compound Library | Radioprotector Library | Mitophagy Compound Library | Bioactive Compound Library Max | MG-132 | Rapamycin | 3-Methyladenine | Doxorubicin hydrochloride | Bafilomycin A1 | Tamoxifen | Y-27632 | LY294002 | Paclitaxel | Z-VAD-FMK | Acetylcysteine | Angiotensin II human | H2DCFDA | 2-Deoxy-D-glucose | Staurosporine | Actinomycin D | SB-431542 | 5-Fluorouracil | Bortezomib | Deferoxamine mesylate | Oxaliplatin | Trametinib | Sorafenib | MitoSOX Red | ATP | Retinoic acid | Temozolomide | Gemcitabine | Decitabine | Mdivi-1 品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物；10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；设有专业的实验中心和严格的质控、验证体系；提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；产品的生物活性多经各国客户实验验证；Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；与世界各大制药公司及知名科研机构建立了长期的合作。