Sozinibercept 产品活性：Sozinibercept (OPT 302; VGX-300) 是 VEGFR-3 的可溶性形式，能有效抑制血管生成原因子 VEGF-C/D 的活性，抑制血管生成和血管渗漏。Sozinibercept 对大鼠糖尿病视网膜水肿也有抑制作用。 产品来源： https://www.medchemexpress.cn/sozinibercept.html 研究领域：Protein Tyrosine Kinase/RTK 作用靶点：VEGFR In Vivo: Sozinibercept inhibits CNV lesion formation and vascular leakage in the mouse laser-induced model of choroidal neovascularization (CNV). Moreover, Sozinibercept exhibits comparable efficacy to Aflibercept (HY-108801; Eylea®) in CNV mouse model. Sozinibercept (intravitreal injection; once every 4 wk for 4 months) shows selective inhibition of VEGF-C/D, and inhibits diabetic retinal edema induced by streptozotocin (STZ) in the rat model, and equivalent to inhibition of VEGF-A inhibitor (Aflibercept). 相关产品：Drug Repurposing Compound Library Plus | Clinical Compound Library Plus | Bioactive Compound Library Plus | Antibody Inhibitor Library | Sorafenib | Lenvatinib | Bevacizumab | Regorafenib | Sunitinib | Nintedanib | Semaxinib | Cabozantinib | Ponatinib | Axitinib | Midostaurin | Chloramphenicol | Pazopanib | Glycine | PD173074 | Tanshinone IIA | Fruquintinib | 5Z-7-Oxozeaenol | Vandetanib | SU 5402 | Linifanib | Foretinib | SPHINX31 | Ripretinib | GW806742X | Dovitinib 品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物；10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；设有专业的实验中心和严格的质控、验证体系；提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；产品的生物活性多经各国客户实验验证；Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；与世界各大制药公司及知名科研机构建立了长期的合作。