Ingenol 3,20-dibenzoate 产品活性：Ingenol 3,20-dibenzoate 是一种有效的蛋白激酶C (PKC) 亚型选择性激动剂。Ingenol 3,20-dibenzoate 诱导 nPKC-delta、-epsilon 和 -theta 和 PKC-mu 从胞质部分选择性转移到颗粒组分，并通过从头合成大分子诱导形态上典型的凋亡 (apoptosis)。Ingenol 3,20-dibenzoate 可促进 NK 细胞产生 IFN-γ 和脱颗粒，尤其是当 NSCLC 细胞刺激 NK 细胞时。 产品来源： https://www.medchemexpress.cn/ingenol-3-20-dibenzoate.html 研究领域：Epigenetics | TGF-beta/Smad | Apoptosis 作用靶点：PKC | Apoptosis 来源：植物 | 大戟科 | 乳浆大戟 结构分类：萜类 | 二萜 In Vitro: Ingenol 3,20-dibenzoate (0-10000 nM; 4 hours) enhanced NK cells (stimulated by A549 cells and H1299 cells) degranulation.? Ingenol 3,20-dibenzoate (0.001-10 μg/ml) dose dependently promoted UT-7/EPO cell proliferation with an EC50 of 0.27 μg/ml (485 nM). In Vivo: Ingenol 3,20-dibenzoate (20 μg/mouse; i.p.; on days 3, 7, and 11) lessens the anemia induced by 5-fluorouracil in an in vivo mouse model. 相关产品：Natural Product Library Plus | Bioactive Compound Library Plus | Apoptosis Compound Library | Epigenetics Compound Library | Immunology/Inflammation Compound Library | TGF-beta/Smad Compound Library | Natural Product Library | CNS-Penetrant Compound Library | Oxygen Sensing Compound Library | Terpenoids Library | Cytoskeleton Compound Library | Traditional Chinese Medicine Active Compound Library | Anti-Lung Cancer Compound Library | Anti-Cancer Natural Product Library | Anti-inflammatory Traditional Chinese Medicine Active Compound Library | Plant-Sourced Natural Product Library | Coagulation and Anti-coagulation Compound Library | Membrane Protein-targeted Compound Library | Highly Selective Activators Library | Cell Death Library | Bioactive Compound Library Max | MG-132 | Phorbol 12-myristate 13-acetate | Doxorubicin hydrochloride | Bafilomycin A1 | Tamoxifen | Y-27632 | LY294002 | Paclitaxel | Z-VAD-FMK | Acetylcysteine | Angiotensin II human | 2-Deoxy-D-glucose | Forskolin | Staurosporine | Actinomycin D | SB-431542 | 5-Fluorouracil | Bortezomib | Deferoxamine mesylate | Oxaliplatin | Trametinib | Sorafenib | Temozolomide | Gemcitabine | Decitabine | Mdivi-1 | Rotenone | Etoposide | Elesclomol | Ruxolitinib 品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物；10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；设有专业的实验中心和严格的质控、验证体系；提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；产品的生物活性多经各国客户实验验证；Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；与世界各大制药公司及知名科研机构建立了长期的合作。