耗材描述
β-Bisabolene
产品活性:β-Bisabolene 是从芍药 (Commiphora guidotti) 中分离得到的倍半萜。β-Bisabolene 是一种抗肿瘤试剂 (anti-cancer agent),可用于乳腺癌的研究。
产品来源: https://www.medchemexpress.cn/β-bisabolene.html
研究领域:Others
作用靶点:Others
来源:植物 | 其他科
结构分类:萜类 | 倍半萜 | 结构分类
In Vitro: β-Bisabolene exhibits selective cytotoxic activity for mouse cells, it against normal Eph4, MG1361 and 4T1 cells with IC50 values of >200 µg/ml, 65.49 µg/ml, and 48.99 µg/ml, respectively. It against normal MCF-10A, MCF-7, MDA-MB-231, SKBR3 and BT474 cells with IC50 values of 114.3 µg/mL, 66.91 µg/mL, 98.39 µg/mL, 70.62 µg/mL and 74.3 µg/mL, respectively.
In Vivo: β-Bisabolene is effective in reducing the growth of transplanted 4T1 mammary tumours in vivo (37.5% reduction in volume by endpoint).
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