Coenzyme FO 产品活性：Coenzyme FO 是一种脱氮黄素发色团，在产甲烷途径中起着重要的氢化物受体/供体作用。 产品来源： https://www.medchemexpress.cn/coenzyme-f420-1.html 研究领域：Anti-infection | Metabolic Enzyme/Protease 作用靶点：Bacterial | Endogenous Metabolite 结构分类：其他类 | 结构分类 In Vitro: The formation of Coenzyme FO is mediated by two separate radical SAM active sites, one each in the CofG and CofH enzymes or both in the FbiC enzyme. These two radical SAM domains constitute the functional domains of Fo synthase. F420 is biosynthesized in Methanocaldococcus jannaschii by the action of eight enzymes with the formation of the deazaflavin chromophore (Fo) as the remaining unsolved step. Coenzyme F420 is the central low-redox-potential electron carrier in methanogenic metabolism. Coenzyme F420 is reduced under hydrogen by the action of F420-dependent hydrogenase. Coenzyme F420 acts as a hydride transfer coenzyme for an F420-specific glucose-6-phosphate dehydrogenase (Fgd) in mycobacteria. Coenzyme F420 is found in all methanogenic and certain nonmethanogenic archaea, where it participates in energy metabolism, NADP reduction, oxygen detoxification, and sulfite reduction. By converting NO2 back to NO with F420H2, M. tuberculosis could decrease the effectiveness of antibacterial action of macrophages. 相关产品：Natural Product Library Plus | Bioactive Compound Library Plus | Rapamycin | 3-Methyladenine | Doxorubicin hydrochloride | Bafilomycin A1 | Dimethyl sulfoxide | Dexamethasone | Acetylcysteine | Puromycin dihydrochloride | Staurosporine | Actinomycin D | 5-Fluorouracil | ATP | Retinoic acid | Etoposide | G-418 disulfate | Hydrocortisone | Nigericin sodium salt | 5-Azacytidine | Brefeldin A | CCCP | Estradiol | Nicotinamide | Prostaglandin E2 | AICAR | Ionomycin | Hygromycin B | Palmitic acid | Docetaxel | Mitomycin C | Isoprenaline hydrochloride 品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物；10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；设有专业的实验中心和严格的质控、验证体系；提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；产品的生物活性多经各国客户实验验证；Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；与世界各大制药公司及知名科研机构建立了长期的合作。