Reversin 121 产品活性：Reversin 121 是一种 P-糖蛋白 (P-glycoprotein) 抑制剂。Reversin 121 增加 MDR1 的 ATP 酶活性。Reversin 121 可逆转 P-糖蛋白 介导的多药耐药性。Reversin 121 可用于癌症研究。 产品来源： https://www.medchemexpress.cn/reversin-121.html 研究领域：Membrane Transporter/Ion Channel 作用靶点：P-glycoprotein In Vitro: Reversin 121 (12 μg/mL) (with gemcitabine (HY-17026)) reduces the proportions of tumor cells positive for MDR proteins in Panc1 cell. Reversin 121 (5 μM) reverses the resistance against paclitaxel in paclitaxel-resistant NCI-H460 cell. Reversin 121 (10 μM, 48 h) inhibits T cell proliferation. In Vivo: Reversin 121 (2.5 mg/kg, plus 5-fluorouracil, 35 mg/kg/day, i.p.) decreases tumor size and prevalence of metastases. 相关产品：Bioactive Compound Library Plus | Membrane Transporter/Ion Channel Compound Library | Anti-Cancer Compound Library | Peptide Library | Cancer Stem Cells Compound Library | Membrane Protein-targeted Compound Library | Anti-Drug-Resistant Compound Library | Anti-Ovarian Cancer Compound Library | Bioactive Compound Library Max | Verapamil | Elacridar | Tariquidar | Glibenclamide | Zosuquidar trihydrochloride | Piperine | Risperidone | CP-100356 hydrochloride | Limonin | Trifluoperazine dihydrochloride | Valspodar | Paris saponin VII | Atazanavir sulfate | Solamargine | Encequidar | Dofequidar fumarate | Moxidectin | Sinapine | (20S)-Protopanaxadiol | Reversan | Selamectin | Isosinensetin | TTT-28 品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物；10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；设有专业的实验中心和严格的质控、验证体系；提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；产品的生物活性多经各国客户实验验证；Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；与世界各大制药公司及知名科研机构建立了长期的合作。