Virodhamine 产品活性：Virodhamine 是一种内源性大麻素，它通过激活大麻素 (CB) 受体调节神经传递。Virodhamine 是 CB1 受体的拮抗剂和 CB2 受体的激动剂。Virodhamine 通过触发 MAPK 信号和 ROS 的产生诱导巨核细胞分化。 Virodhamine 可用于治疗各种神经疾病，如阿尔茨海默病和帕金森。 产品来源： https://www.medchemexpress.cn/virodhamine.html 研究领域：Metabolic Enzyme/Protease | Neuronal Signaling | GPCR/G Protein 作用靶点：Endogenous Metabolite | Cannabinoid Receptor 结构分类：生物碱 | 其他类生物碱 | 结构分类 In Vitro: Virodhamine (50 nM; 72 h) increases adherence, membrane expansion and the size of nucleus. Virodhamine (10-40 μM; 72 h) increases the expression level of CD61 and TRPV1. Virodhamine (72 h) inhibits the cell proliferation of megakaryocyte cells and significantly increases the portion of high ploidy cells as compared to control. Virodhamine significantly increases the protein expression level of CB2 receptorn, ROS production and NAPDH oxidase NOX4 expression in megakaryocytic cells. In Vivo: Virodhamine (1-10 mg/kg; i.p. once) repairs the nicotine (0.8 mg/kg) and immobilization stress induced anxiety in vivo. 相关产品：Natural Product Library Plus | Bioactive Compound Library Plus | GPCR/G Protein Compound Library | Metabolism/Protease Compound Library | Neuronal Signaling Compound Library | Natural Product Library | Lipid Compound Library | Anti-Alzheimer's Disease Compound Library | Alkaloids Library | Anti-Parkinson's Disease Compound Library | Neurodegenerative Disease-related Compound Library | Pain-Related Compound Library | Membrane Protein-targeted Compound Library | Membrane Receptor-targeted Compound Library | Bioactive Compound Library Max | Rapamycin | 3-Methyladenine | Acetylcysteine | 5-Fluorouracil | ATP | Retinoic acid | Hydrocortisone | Estradiol | Nicotinamide | Prostaglandin E2 | AICAR | Palmitic acid | Docetaxel | Isoprenaline hydrochloride | L-Ascorbic acid | Cytarabine | Melatonin | Calcitriol | Capsaicin | Arachidonic acid | Valproic acid | Oleic acid | β-Nicotinamide mononucleotide | Acetaminophen | Biotin | Corticosterone | Lactate | Cholesterol | NAD+ | DHEA 品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物；10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；设有专业的实验中心和严格的质控、验证体系；提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；产品的生物活性多经各国客户实验验证；Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；与世界各大制药公司及知名科研机构建立了长期的合作。