Vanillylmandelic acid 产品活性：Vanillylmandelic acid 是肾上腺素和去甲肾上腺素代谢的最终产物。Vanillylmandelic acid 也可作为神经递质代谢紊乱的标志物。Vanillylmandelic acid 具有抗氧化 (antioxidant) 活性，清除 DPPH 自由基的 IC50 值为 33 μM。 产品来源： https://www.medchemexpress.cn/vanillylmandelic-acid.html 研究领域：Metabolic Enzyme/Protease 作用靶点：Endogenous Metabolite 结构分类：酚类 | 单酚类 | 酮、醛、酸 | 结构分类 In Vitro: Vanillylmandelic acid has antioxidant activity, the IC50 value is determined as the amount of VMA required to reduce 50% of the starting concentration of free radical is 33*10-6 M in the UV-Vis decolourisation DPPH assay. In Vivo: Vanillylmandelic acid (intra-arterial injection over 1 min; 1, 10 and 100 mg/kg; the 60 min-observation period) produces a significant difference between vanillylmandelic acid groups and controls. Vanillylmandelic acid decreases the heart rate by 17.5%, 17.9% and 18.9% after 1, 10 and 100 mg/kg, respectively. Mean blood pressure is decreased by 13.5% in control animals as compared to 37%, 23% and 26% after 1, 10 and 100 mg/kg, respectively, in wistar rats. 相关产品：Natural Product Library Plus | Bioactive Compound Library Plus | Metabolism/Protease Compound Library | Natural Product Library | Human Endogenous Metabolite Compound Library | Antioxidant Compound Library | Anti-Cardiovascular Disease Compound Library | Phenols Library | Gut Microbial Metabolite Library | Microbial Metabolite Library | Food-Sourced Compound Library | Drug Metabolite Library | Human Metabolite Library | Coagulation and Anti-coagulation Compound Library | Animal-Sourced Natural Product Library | Multi-Target Compound Library | Radioprotector Library | Bioactive Compound Library Max | Rapamycin | 3-Methyladenine | Acetylcysteine | 5-Fluorouracil | ATP | Retinoic acid | Hydrocortisone | Estradiol | Nicotinamide | Prostaglandin E2 | AICAR | Palmitic acid | Docetaxel | Isoprenaline hydrochloride | L-Ascorbic acid | Cytarabine | Melatonin | Calcitriol | Capsaicin | Arachidonic acid | Valproic acid | Oleic acid | β-Nicotinamide mononucleotide | Acetaminophen | Biotin | Corticosterone | Lactate | Cholesterol | NAD+ | DHEA 品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物；10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；设有专业的实验中心和严格的质控、验证体系；提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；产品的生物活性多经各国客户实验验证；Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；与世界各大制药公司及知名科研机构建立了长期的合作。