Cymarin 产品活性：Cymarin 是一种强心苷，能有效地抑 Palytoxin (PTX) 诱导的 K+ 释放 (IC50=0.42 μM)。Cymarin 对乳腺癌和胰腺癌具有抗肿瘤活性。Cymarin 作为作物保护剂具有拒食和生长抑制作用。 产品来源： https://www.medchemexpress.cn/cymarin.html 研究领域：Others | Anti-infection 作用靶点：Others | Parasite 来源：植物 | 夹竹桃科 | 罗布麻属 结构分类：甾体类 | 强心苷类 | 结构分类 In Vitro: Cymarin (0.25-1 μM) inhibites PAX6 expression by blocking IRES-directed translation and inhibits 47.8% proliferation of MCF-7 cells with the concentration of 1 μM . Cymarin downregulates UGT1A10 expression, eliminates TRA-1-60 (IC50 of 15.2 nM) and TRA-1-81 cells (IC50 of 5.1 nM) in cell lines SW1990GR, inhibits proliferations and cell viabilities of pancreatic cancer cells SW1990 and SW1990GR (IC50 of 33.8 nM for SW1990 and 40.8 for SW1990GR). In Vivo: Cymarin inhibits growth of neonate Trichoplusia ni larvae with EC50 of 157 p.p.m, reveals an antifeedant effect against Trichoplusia ni larva with a DC50 of 10.8 μg/cm2. Cymarin (2 mg/kg, i.p., twice a week for 3 weeks) inhibits tumor growth, eliminates TRA-1-60 cells and decreases chemoresistance in SW1990 xenografted nude mice. 相关产品：Chloroquine | Puromycin dihydrochloride | Hygromycin B | Doxycycline hyclate | Digitonin | Acetaminophen | Anisomycin | 5-Ph-IAA | FLAG peptide | Metronidazole | Kaempferol | 3X FLAG peptide | TCEP hydrochloride | Monocrotaline | Tocofersolan | Amphotericin B | Pronase E (Activity ≥ 7000 U/g) | Hydroxychloroquine | DPPH | DNase I, Bovine pancreas | Monensin sodium | Dihydroartemisinin | NMDI14 | Niclosamide | O-Propargyl-Puromycin | Berberine chloride | Human IgG1 kappa, Isotype Control 品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物；10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；设有专业的实验中心和严格的质控、验证体系；提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；产品的生物活性多经各国客户实验验证；Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；与世界各大制药公司及知名科研机构建立了长期的合作。