Masoprocol 产品活性：Masoprocol (meso-Nordihydroguaiaretic acid) 是一种有效且具有口服活性的脂氧合酶 (lipoxygenase) 抑制剂。Masoprocol 显示出抗高血糖活性。 Masoprocol 降低体内葡萄糖浓度和肝脏甘油三酯浓度。Masoprocol具有研究II型糖尿病的潜力。 产品来源： https://www.medchemexpress.cn/masoprocol.html 研究领域：Metabolic Enzyme/Protease 作用靶点：Lipoxygenase 来源：植物 | 其他科 结构分类：酚类 | 多酚类 In Vitro: Masoprocol (30 µM; 90 min) shows high basal and insulin-stimulated glucose clearance in adipocytes. In Vivo: Masoprocol (150 mg/kg; i.g.; twice a day for 12 days) shows antihyperglycemic activity with the decreases in glucose concentration in plasma in male C57BL/ks-db/db mice. Masoprocol （0.83 mmol/kg; twice a day for 4 days）shows low glucose concentrations an average of 35% and low triglyceride concentrations of 80% compared with the vehicle at a rat model of type II diabetes. Masoprocol (40-80 mg/kg; p.o.; twice daily for 8 days) significantly reduces hepatic triglyceride (TG) secretion (P<.01) and liver TG content in a nondiabetic rat model with dietary-induced hypertriglyceridemia(HTG). 相关产品：Natural Product Library Plus | Drug Repurposing Compound Library Plus | FDA-Approved Drug Library Plus | FDA-Approved Drug Library Mini | Bioactive Compound Library Plus | Immunology/Inflammation Compound Library | Metabolism/Protease Compound Library | Natural Product Library | FDA-Approved Drug Library | Drug Repurposing Compound Library | Anti-diabetic Compound Library | Ferroptosis Compound Library | Phenols Library | Traditional Chinese Medicine Active Compound Library | FDA Approved & Pharmacopeial Drug Library | Lipid Metabolism Compound Library | Anti-inflammatory Traditional Chinese Medicine Active Compound Library | Plant-Sourced Natural Product Library | Human Metabolite Library | Non-steroidal Anti-Inflammatory Compound Library | Off-patent Drug Library | Metabolic Enzyme Compound Library | Mitochondrial Toxicity Compound Library | FDA-Approved Traditional Chinese Medicine Active Compound Library | Bioactive Compound Library Max | Anti-Fibrosis Compound Library | Cisplatin | U-73122 | Zileuton | Wedelolactone | ML355 | Caffeic acid | Nordihydroguaiaretic acid | ML351 | Psoralidin | Chebulagic acid | Indirubin-3'-monoxime | Licofelone | 4',5-Dihydroxyflavone | Pectolinarigenin | 15-LOX-1 inhibitor 1 | β-Boswellic acid | Cirsiliol | PF-4191834 | 11-​Keto-​beta-​boswellic acid | Osavampator | Tepoxalin | Docebenone | Malotilate | ThioLox | 2,5-Di-tert-butylhydroquinone | 5-O-Demethylnobiletin | ALOX15-IN-2 | FPL 62064 | S-(+)-Marmesin | 4-Nitrocatechol 品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物；10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；设有专业的实验中心和严格的质控、验证体系；提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；产品的生物活性多经各国客户实验验证；Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；与世界各大制药公司及知名科研机构建立了长期的合作。