Delphinidin 3-glucoside chloride 产品活性：Delphinidin 3-glucoside chloride (Delphinidin 3-O-glucoside chloride) 是在 Hibiscus sabdariffa 提取物中发现的一种活性花色苷。Delphinidin 3-glucoside chloride 诱导 B 细胞慢性淋巴细胞性白血病 (B CLL) 的促凋亡作用。Delphinidin 3-glucoside chloride 通过结合 ERβ 发挥植物雌激素活性，IC50 为 9.7 μM。Delphinidin-3-O-glucoside chloride 抑制 EGFR，IC50 为 2.37 µM。Delphinidin 3-glucoside chloride 通过调节 pAKT/IRF1/HOTAIR 通路表达抗肿瘤活性。Delphinidin 3-glucoside chloride 具有抗氧化活性，抑制血小板聚集和内皮细胞功能障碍。 产品来源： https://www.medchemexpress.cn/delphinidin-3-glucoside-chloride.html 研究领域：JAK/STAT Signaling | Protein Tyrosine Kinase/RTK | Apoptosis | PI3K/Akt/mTOR 作用靶点：EGFR | Apoptosis | Akt 来源：植物 | 锦葵科 | 玫瑰茄 结构分类：黄酮类 | 花色素类 | 结构分类 In Vitro: Delphinidin 3-glucoside chloride (30-100 μM) induces cell apoptosis in B CLL cells through redox-sensitive caspase 3 activation. Delphinidin 3-glucoside chloride (0-40 μM) exhibits inhibitory activity towards breast cancer cells and carcinogen-induced breast carcinogenesis, through downregulation of the HOTAIR expression via pAKT/IRF1 signaling pathway. Delphinidin 3-glucoside chloride (1-100 μM) inihibits the oxLDL-induced endothelial dysfunction in HUVECs with dependence of Sodium-Dependent Glucose Transporter (SGLT1). Delphinidin 3-glucoside chloride (0-50 μM) inhibits ADP, collagen or TRAP stimulated platelet aggregation through inhibition of AMPK phosphorylation. In Vivo: Delphinidin 3-glucoside chloride (40 mg/kg/day, i.g. for 25 days) inhibits tumor growth in MDA-MB-231-Luc-GFP xenografted athymic BALB/c mice . Delphinidin 3-glucoside chloride (50 μM, i.v.) inhibits thrombus growth in FeCl3 induced mesenteric arteriole injury in C57BL/6 mice. 相关产品：Natural Product Library Plus | Bioactive Compound Library Plus | Apoptosis Compound Library | Immunology/Inflammation Compound Library | JAK/STAT Compound Library | Kinase Inhibitor Library | PI3K/Akt/mTOR Compound Library | Protein Tyrosine Kinase Compound Library | Stem Cell Signaling Compound Library | Natural Product Library | Anti-Cancer Compound Library | Autophagy Compound Library | Anti-Aging Compound Library | Differentiation Inducing Compound Library | Glycoside Compound Library | Oxygen Sensing Compound Library | Anti-Cardiovascular Disease Compound Library | Medicine Food Homology Compound Library | Glycolysis Compound Library | Cytoskeleton Compound Library | Glutamine Metabolism Compound Library | Traditional Chinese Medicine Active Compound Library | Flavonoids Library | Anti-Hepatitis C Virus Compound Library | Anti-Breast Cancer Compound Library | Anti-Lung Cancer Compound Library | Anti-Pancreatic Cancer Compound Library | Anti-Blood Cancer Compound Library | Anti-Cancer Metabolism Compound Library | Anti-Parkinson's Disease Compound Library | Neurodegenerative Disease-related Compound Library | Anti-Obesity Compound Library | Angiogenesis-Related Compound Library | Glucose Metabolism Compound Library | Food-Sourced Compound Library | Anti-Liver Cancer Compound Library | Anti-Colorectal Cancer Compound Library | Anti-Cancer Natural Product Library | Anti-inflammatory Traditional Chinese Medicine Active Compound Library | Plant-Sourced Natural Product Library | Human Metabolite Library | Anti-Prostate Cancer Compound Library | Anti-Pulmonary Fibrosis Compound Library | Cancer Stem Cells Compound Library | Coagulation and Anti-coagulation Compound Library | Heterocyclic Compound Library | Pain-Related Compound Library | Membrane Protein-targeted Compound Library | Membrane Receptor-targeted Compound Library | Cytokine Inhibitors Library | Cell Death Library | Serine/Threonine Kinase Inhibitor Library | Anti-Hematopathy Compound Library | Anti-Ovarian Cancer Compound Library | Multi-Target Compound Library | Bioactive Compound Library Max | Anti-Gastric Cancer Compound Library | Anti-Fibrosis Compound Library | MG-132 | Doxorubicin hydrochloride | Bafilomycin A1 | Tamoxifen | Y-27632 | LY294002 | Paclitaxel | Z-VAD-FMK | Acetylcysteine | Angiotensin II human | 2-Deoxy-D-glucose | Staurosporine | Actinomycin D | SB-431542 | 5-Fluorouracil | Bortezomib | Deferoxamine mesylate | Oxaliplatin | Trametinib | Sorafenib | Temozolomide | Gemcitabine | Decitabine | Osimertinib | Mdivi-1 | Rotenone | Etoposide | Elesclomol | Ruxolitinib | Monomethyl auristatin E 品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物；10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；设有专业的实验中心和严格的质控、验证体系；提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；产品的生物活性多经各国客户实验验证；Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；与世界各大制药公司及知名科研机构建立了长期的合作。