Dihydro-β-erythroidine hydrobromide 产品活性：Dihydro-β-erythroidine (DHβE) hydrobromide 是一种有效竞争性的，具有口服活性的神经 nAChRs 拮抗剂。Dihydro-β-erythroidine hydrobromide 对 α4β4 和 α4β2 有选择性，IC50 分别为 0.19 和 0.37 μM。具有抗抑郁类活性。 产品来源： https://www.medchemexpress.cn/dihydro-β-erythroidine-hydrobromide.html 研究领域：Membrane Transporter/Ion Channel | Neuronal Signaling 作用靶点：nAChR 来源：植物 | 豆科 | 刺桐属 结构分类：生物碱 | 哌啶类生物碱 | 结构分类 In Vivo: Dihydro-Beta-Erythroidine hydrobromide (DHβE hydrobromide; 10 nmol/0.5?μL) is infused into the respective areas prior to a systemic nicotine injection (0.2?mg/kg; SC). DHβE infused into the ventral tegmental area (VTA), nucleus accumbens (NAcc), or infralimbic (IL)? cortex, but not prelimbic (PrL) cortex, attenuated nicotine-enhanced responding for a conditioned reinforcer (CRf).? The co-administration of Dihydro-Beta-Erythroidine hydrobromide (5.0 mg/kg; s.c) with nicotine (0.2 and 0.4 mg/kg; s.c.) prevents the development of conditioned taste aversions (CTAs). 相关产品：Natural Product Library Plus | Bioactive Compound Library Plus | Membrane Transporter/Ion Channel Compound Library | Neuronal Signaling Compound Library | Natural Product Library | Neurotransmitter Receptor Compound Library | FDA Approved & Pharmacopeial Drug Library | Alkaloids Library | Anti-Parkinson's Disease Compound Library | Neurodegenerative Disease-related Compound Library | Antidepressant Compound Library | Plant-Sourced Natural Product Library | Heterocyclic Compound Library | Membrane Protein-targeted Compound Library | Membrane Receptor-targeted Compound Library | Ion Channel Compound Library | Bioactive Compound Library Max | Acetylcholine chloride | Methyllycaconitine citrate | PNU-282987 | Carbamoylcholine chloride | GTS-21 dihydrochloride | Mecamylamine hydrochloride | Choline chloride | Benzethonium chloride | COG 133 TFA | D-Tubocurarine chloride pentahydrate | α-Bungarotoxin | Arecoline hydrobromide | Varenicline | Spinosad | Anabasine | PNU-120596 | Rocuronium Bromide | Levamisole | Hydroxybupropion | Lobeline hydrochloride | Monepantel | Cisatracurium besylate | Dequalinium Chloride | Hexamethonium Bromide | Pancuronium dibromide | PHA-543613 | Vecuronium bromide | Adiphenine hydrochloride 品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物；10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；设有专业的实验中心和严格的质控、验证体系；提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；产品的生物活性多经各国客户实验验证；Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；与世界各大制药公司及知名科研机构建立了长期的合作。