耗材描述
Davunetide
产品活性:Davunetide 是一种八个氨基酸多肽,来源于活性依赖性神经保护蛋白 (ADNP),一种存在于哺乳动物中枢神经系统中的神经营养因子。Davunetide 具有神经保护、神经营养和认知保护特性。Davunetide 是一种微管稳定肽 (microtubule-stabilizing),在体外与神经元特异性βIII微管蛋白相互作用并稳定其活性。Davunetide 可透过血脑屏障,无毒。Davunetide 抑制Aβ聚集和Aβ诱导的神经毒性。
产品来源: https://www.medchemexpress.cn/davunetide.html
研究领域:Cell Cycle/DNA Damage | Cytoskeleton | Neuronal Signaling
作用靶点:Microtubule/Tubulin | Amyloid-β
In Vivo: Davunetide (2 μg/kg; Intranasally; daily, 5 days a week, for 16 weeks) shows protective effects for central nervous system complications in a diabetes rat model.
相关产品:Drug Repurposing Compound Library Plus | Clinical Compound Library Plus | Bioactive Compound Library Plus | Cell Cycle/DNA Damage Compound Library | Neuronal Signaling Compound Library | Clinical Compound Library | Anti-Aging Compound Library | Drug Repurposing Compound Library | Anti-diabetic Compound Library | Cytoskeleton Compound Library | Anti-Alzheimer's Disease Compound Library | Neuroprotective Compound Library | Anti-Lung Cancer Compound Library | Neurodegenerative Disease-related Compound Library | Rare Diseases Drug Library | Peptide Library | Heterocyclic Compound Library | Membrane Protein-targeted Compound Library | Highly Selective Inhibitors Library | Multi-Target Compound Library | Bioactive Compound Library Max | Paclitaxel | Monomethyl auristatin E | DAPT | VcMMAE | Docetaxel | Nocodazole | Vincristine sulfate | Colchicine | Mertansine | β-Amyloid (25-35) | Thioflavin T | β-Amyloid (1-42), human TFA | MMAF | FPS-ZM1 | Rutin | Vinblastine sulfate | 2-Methoxyestradiol | DM4 | Vinorelbine ditartrate | Eribulin mesylate | Colivelin TFA | Sovilnesib | Azeliragon | Cabazitaxel | Santacruzamate A | Demecolcine | 20(S)-Ginsenoside Rg3 | Ginsenoside Rg1
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