耗材描述
Capsaicin (Purity 65%)
产品活性:Capsaicinoid (65%Capsaicin) 是辣椒素和二氢辣椒素的混合物,是一种具有口服活性的辣椒素受体 (TRPV1) 激动剂。
产品来源: https://www.medchemexpress.cn/capsaicin-purity-99.html
研究领域:Membrane Transporter/Ion Channel | Neuronal Signaling | Autophagy | Apoptosis | Metabolic Enzyme/Protease
作用靶点:TRP Channel | Autophagy | Apoptosis | Endogenous Metabolite
来源:植物 | 茄科 | 辣椒
结构分类:酚类 | 单酚类 | 结构分类
In Vitro: Capsaicin is the main Capsaicinoid in chili peppers, followed by Dihydrocapsaicin. These two compounds provide about twice hotness to the taste and nerves as the minor capsaicinoids.
In Vivo: Capsaicin (Purity 65%) (1-10 mg/kg, oral gavage) increases chlorzoxazone 6-hydroxylase activity and the expression of CYP2E1 in liver microsomes of rats.
Capsaicin (Purity 65%) (10 mg/kg, s.c.) shows the Cmax of 104.9 ng/mL for Capsaicin and 54.3 ng/mL for Dihydrocapsaicin, the Tmax of 5 h for Capsaicin and 4 h for Dihydrocapsaicin.
Capsaicin is more pungent than Dihydrocapsaicin (HY-N0361).
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