Latrunculin B 产品活性：Latrunculin B 是一种抗菌生物碱，是一种肌动蛋白聚合 (actin polymerization) 抑制剂。Latrunculin B 调节肺静脉电生理特征并减轻牵张性心律失常的发生。抗真菌和抗原生动物活性。 产品来源： https://www.medchemexpress.cn/latrunculin-b.html 研究领域：Anti-infection 作用靶点：Fungal In Vitro: Latrunculin B displays growth inhibition of HeLa cells with an IC50 value of 1.4 μM. Latrunculin B modulates electrophysiological characteristics and arrhythmogenesis in pulmonary vein cardiomyocytes. Latrunculin B (100 nM) decreases the spontaneous electrical activity by 16±4% in pulmonary vein (PV) preparations. Latrunculin B (100 nM) decreases the late Na+ current, L-type Ca2+ current, Na+/Ca2+ exchanger current, and stretch-activated BKCa current in PV cardiomyocytes. Latrunculin B reduces the transient outward K+ current and ultra-rapid delayed rectifier K+ current, but increases the delayed rectifier K+ current in isolated PV cardiomyocytes. Latrunculin B (100 nM) decreases intracellular Ca2+ transient and sarcoplasmic reticulum Ca2+ content in PV cardiomyocytes. Latrunculin B attenuates stretch-induced increased spontaneous electrical activity and trigger activity. 相关产品：Rapamycin | Ferrostatin-1 | Cycloheximide | Staurosporine | Hygromycin B | Resveratrol | Tunicamycin | Oligomycin | Camptothecin | Filipin complex | Amphotericin B | Calcimycin | Monensin sodium | Nystatin | Ketoconazole | Itraconazole | Fluconazole | Valinomycin | Tofacitinib citrate | Caspofungin diacetate | Mycophenolic acid | Leptomycin B | Idarubicin hydrochloride | Toyocamycin | Terbinafine | Hyperoside | Saponins | Sinefungin | Carvacrol 品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物；10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；设有专业的实验中心和严格的质控、验证体系；提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；产品的生物活性多经各国客户实验验证；Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；与世界各大制药公司及知名科研机构建立了长期的合作。