耗材描述
Nanchangmycin
产品活性:Nanchangmycin 由 Streptomyces nanchangensis NS3226 产生的一种聚醚抗生素,抑制革兰氏阳性菌。Nanchangmycin 也是一种抗 Zika 病毒的广谱抗病毒活性分子。
产品来源: https://www.medchemexpress.cn/Nanchangmycin.html
研究领域:Anti-infection
作用靶点:Bacterial | Antibiotic | Flavivirus
结构分类:抗生素 | 疾病研究 | 抗菌 | 抗生素 | 疾病研究 | 抗病毒 | 抗生素 | 聚醚类 | 结构分类
In Vitro: Nanchangmycin can be used as a growth promotant in poultry and to cure coccidiosis in chickens. Nanchangmycin is active against drug resistant strains of malaria. Nanchangmycin as a potent inhibitor of Zika virus (ZIKV) entry across all cell types tested including physiologically relevant primary cells. Nanchangmycin potently reduces infection of all three strains of ZIKV across all three cell types. The IC50s for infection are between 0.1 and 0.4 μM while Nanchangmycin has low toxicity in these ranges. In addition, DENV is inhibited by Nanchangmycin across cell types.
相关产品:Covalent Screening Library Plus | Natural Product Library Plus | Bioactive Compound Library Plus | Anti-Infection Compound Library | Natural Product Library | Covalent Screening Library | Antibacterial Compound Library | Antibiotics Library | Microbial Metabolite Library | Heterocyclic Compound Library | Bioactive Compound Library Max | Rapamycin | Cycloheximide | Chloroquine | Doxorubicin hydrochloride | Bafilomycin A1 | Dimethyl sulfoxide | Dexamethasone | Puromycin dihydrochloride | Staurosporine | Actinomycin D | Etoposide | G-418 disulfate | Nigericin sodium salt | Cyclosporin A | 5-Azacytidine | Brefeldin A | CCCP | Estradiol | Bleomycin sulfate | Ionomycin | Hygromycin B | Mitomycin C | Resveratrol | Tunicamycin | Everolimus | Doxycycline hyclate | Tacrolimus | Oligomycin
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