Amitriptyline-d6 hydrochloride 产品活性：Amitriptyline-d6 (hydrochloride) 是 Amitriptyline hydrochloride 的氘代物。Amitriptyline hydrochloride 是一种血清素再摄取转运体 (SERT) 和去甲肾上腺素再摄取转运体 (NET) 抑制剂，对人的 SERT 和 NET 作用的 Ki 值分别为 3.45 nM 和 13.3 nM。Amitriptyline hydrochloride 还与多巴胺再摄取转运体 (DAT) 结合，其 Ki 为 2.58 μM。Amitriptyline hydrochloride 也抑制肾上腺素能受体 (adrenergic receptor)、毒蕈碱受体 (muscarinic receptor )、组胺受体 (histamine receptor )、5-羟色胺受体 (5-HT receptor)。Amitriptyline hydrochloride 是一种具有强神经营养活性的 TrkA 和 TrkA 受体激动剂。Amitriptyline hydrochloride 具有抗抑郁作用。 产品来源： https://www.medchemexpress.cn/amitriptyline-d6-hydrochloride.html 研究领域：Neuronal Signaling | Immunology/Inflammation | GPCR/G Protein | Membrane Transporter/Ion Channel | Protein Tyrosine Kinase/RTK 作用靶点：Serotonin Transporter | 5-HT Receptor | Histamine Receptor | mAChR | Adrenergic Receptor | Sodium Channel | Trk Receptor In Vitro: Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs. 相关产品：Isoprenaline hydrochloride | Clozapine N-oxide | Norepinephrine | Deschloroclozapine | Pilocarpine Hydrochloride | Histamine | Zenidolol hydrochloride | Amiloride hydrochloride | Propranolol hydrochloride | Phenylephrine | Entrectinib | CL 316243 | Chlorpromazine hydrochloride | Serotonin hydrochloride | SCH-23390 hydrochloride | Atropine | Harmine | D-Mannitol | Puerarin | Halofuginone | Fluoxetine hydrochloride | Sertraline hydrochloride | Metoprolol | Desipramine hydrochloride | L-Epinephrine 品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物；10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；设有专业的实验中心和严格的质控、验证体系；提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；产品的生物活性多经各国客户实验验证；Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；与世界各大制药公司及知名科研机构建立了长期的合作。