Dronedarone D6 hydrochloride 产品活性：Dronedarone-d6 (hydrochloride) 是 Dronedarone 的氘代物。Dronedarone (SR 33589) hydrochloride 是胺碘酮 (HY-14187) 的衍生物，是一种用于研究心房颤动 (AF) 的 class III 抗心律失常的试剂 (antiarrhythmic agent)。Dronedarone hydrochloride 是多种离子电流 (ion currents) 的有效阻滞剂，包括钾电流，钠电流，和 L 型钙电流，并通过非竞争性结合到肾上腺素能受体显示出抗肾上腺素能的效果。Dronedarone hydrochloride 是 CYP3A4 的底物和中度抑制剂。 产品来源： https://www.medchemexpress.cn/dronedarone-d6-hydrochloride.html 研究领域：GPCR/G Protein | Neuronal Signaling | Membrane Transporter/Ion Channel | Metabolic Enzyme/Protease | Autophagy 作用靶点：mAChR | Sodium Channel | Calcium Channel | Adrenergic Receptor | Cytochrome P450 | Autophagy In Vitro: Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs. 相关产品：Thapsigargin | Ionomycin | Isoprenaline hydrochloride | L-Ascorbic acid | Clozapine N-oxide | Norepinephrine | Deschloroclozapine | Minocycline hydrochloride | Pilocarpine Hydrochloride | Verapamil | 2-Aminoethyl diphenylborinate | Acetylcholine chloride | Apigenin | Zenidolol hydrochloride | Fenofibrate | Amiloride hydrochloride | Propranolol hydrochloride | Phenylephrine | GSK1016790A | CL 316243 | Chlorpromazine hydrochloride | Nifedipine | Ketoconazole | Abiraterone | Fasudil Hydrochloride | Letrozole | 1-Aminobenzotriazole | Ebselen 品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物；10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；设有专业的实验中心和严格的质控、验证体系；提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；产品的生物活性多经各国客户实验验证；Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；与世界各大制药公司及知名科研机构建立了长期的合作。