WAY-262611 产品活性：WAY-262611是 Wnt/β- 联蛋白激动剂，可增加骨形成速率，在 TCF- 荧光素酶测定实验中的 EC50 值为0.63 μM。WAY-262611 也是 Dkk1 的抑制剂。 产品来源： https://www.medchemexpress.cn/WAY-262611.html 研究领域：Stem Cell/Wnt 作用靶点：β-catenin In Vitro: WAY-262611 has the most potent activity in the primary assay, low kinase inhibition potential, and high solubility. In Vivo: WAY-262611 has excellent pharmacokinetic properties and shows a dose dependent increase in the trabecular bone formation rate in ovariectomized rats following oral administration. Calvariae from wt mice treated with WAY-262611 shows statistically increased BFR, while similarly treated KO animals are no different from control. This indicates that WAY-262611 is acting via the Wnt β-catenin pathway and most likely through inhibition of Dkk-1. 相关产品：Bioactive Compound Library Plus | Stem Cell Signaling Compound Library | Wnt/Hedgehog/Notch Compound Library | Anti-Cancer Compound Library | Anti-Aging Compound Library | Reprogramming Compound Library | Cytoskeleton Compound Library | Neuroprotective Compound Library | Anti-Obesity Compound Library | Transcription Factor-Targeted Library | Targeted Diversity Library | Osteogenesis Compound Library | Membrane Protein-targeted Compound Library | Extracellular Vesicles (EVs) Compound Library | Bioactive Compound Library Max | Laduviglusib | XAV-939 | ICG-001 | MSAB | SKL2001 | Salinomycin | Tegatrabetan | LF3 | Toxoflavin | FH535 | Cardamonin | PNU-74654 | HLY78 | Triptonide | NRX-252262 | KYA1797K | ZW4864 | Kaempferide | Laduviglusib (GMP) | (E)-Ferulic acid | Wnt/β-catenin agonist 2 | Mirodenafil dihydrochloride | NRX-103094 | CWP232228 | KY19382 | L-Quebrachitol | NRX-252114 品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物；10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；设有专业的实验中心和严格的质控、验证体系；提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；产品的生物活性多经各国客户实验验证；Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；与世界各大制药公司及知名科研机构建立了长期的合作。