耗材描述
YL-109
产品活性:YL-109是一种抗肿瘤剂,可以通过芳烃受体 AhR 信号传导诱导 Hsp70 相互作用蛋白 (CHIP) 表达。YL-109 具有抑制乳腺癌细胞生长和侵袭性的能力。
产品来源: https://www.medchemexpress.cn/YL-109.html
研究领域:Immunology/Inflammation
作用靶点:Aryl Hydrocarbon Receptor
In Vitro: YL-109 (0.001-10 μM; 96 h or 24 h) inhibits cell proliferation, motility, and invasiveness in breast cancer cells.
YL-109 (1 μM) increases both CHIP mRNA and protein levels in MDA-MB-231 cells.
In Vivo: YL-109 (15 mg/kg; s.c. for every 2 d) inhibits both tumor growth and cancer metastasis of breast cancer cells in vivo.
相关产品:Bioactive Compound Library Plus | Immunology/Inflammation Compound Library | Anti-Cancer Compound Library | Anti-Breast Cancer Compound Library | Transcription Factor-Targeted Library | Protein-protein Interaction Inhibitor Library | Heterocyclic Compound Library | Extracellular Vesicles (EVs) Compound Library | Bioactive Compound Library Max | PD98059 | CH-223191 | Pifithrin-α hydrobromide | L-Kynurenine | FICZ | Stemregenin 1 | Tapinarof | ITE | BAY 2416964 | Indole-3-carbinol | Diosmin | Carbidopa | Indole-3-pyruvic acid | GNF351 | Skatole | Alpha-Naphthoflavone | BAY-218 | VAF347 | β-Naphthoflavone | PDM2 | Benzyl butyl phthalate | D-Kynurenine | AHR antagonist 2 | AHR antagonist 5 | KYN-101 | 6,2',4'-Trimethoxyflavone | AhR agonist 2 | CAY 10465 | MeBIO
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