Raxatrigine 产品活性：Raxatrigine (GSK-1014802) 是钠离子通道Nav1.7有效抑制剂。 产品来源： https://www.medchemexpress.cn/CNV1014802.html 研究领域：Membrane Transporter/Ion Channel 作用靶点：Sodium Channel In Vitro: Like lamotrigine, both GSK2 and GSK3 were able to prevent the deficit in reversal learning produced by PCP, thus confirming their potential in the treatment of cognitive symptoms of schizophrenia. However, higher doses than those required for anticonvulsant efficacy of the drugs were needed for activity in the reversal-learning model, suggesting a lower therapeutic window relative to mechanism-dependent central side effects for this indication. Raxatrigine (GSK-1014802) received orphan-drug designation from the US Food and Drug Administration in July 2013. 相关产品：Amiloride hydrochloride | Halofuginone | Carbamazepine | Riluzole | 20(S)-Ginsenoside Rg3 | Lidocaine | TPC2-A1-P | Veratridine | Fluphenazine dihydrochloride | Amitriptyline hydrochloride | Lamotrigine | A-803467 | QX-314 chloride | 5-(N,N-Hexamethylene)-amiloride | Phenytoin | Triamterene | Ranolazine | Flunarizine dihydrochloride | Benzamil hydrochloride | Suzetrigine | Atomoxetine hydrochloride | Vinpocetine | Zandatrigine | Ropivacaine | PF 05089771 品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物；10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；设有专业的实验中心和严格的质控、验证体系；提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；产品的生物活性多经各国客户实验验证；Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；与世界各大制药公司及知名科研机构建立了长期的合作。